Indications
Doctors prescribe Pridinol Mesilate for muscle tension and muscle spasm, whether the spasm is central or peripheral in origin. It is also used for neck spasm (torticollis), low back pain (lumbago) and general muscle pain.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Pridinol has a central muscle relaxant effect. It works mainly on the central nervous system (CNS), in the brainstem and the spinal cord, where it selectively inhibits polysynaptic reflexes. In simple terms, when a muscle is injured or strained, the nervous system keeps sending hyperactive signals, and the muscle stays locked in a painful contraction (spasm). Pridinol dampens these overactive reflexes and blocks the excessive signals travelling from the spine to the muscles. The skeletal muscles can then relax, and the localized tension eases.
Pridinol also has an anticholinergic (antimuscarinic) action. It acts as an antagonist to acetylcholine, a primary neurotransmitter that triggers muscle contractions. By blocking the muscarinic acetylcholine receptors, it directly counters the chemical signals that set off muscle spasms in both smooth and skeletal muscles. This is also why it helps reduce the muscle rigidity and tremors associated with parkinsonism.
Pregnancy & Breastfeeding
Pridinol should not be taken in the first 3 months of pregnancy. In the months after that, it may be taken only if it's necessary, and only after careful thought under a doctor's supervision. No data is available on whether Pridinol passes into human milk, so it's best to avoid it while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.