Indications
Pilo Drop is used to treat chronic open-angle glaucoma, acute or chronic narrow-angle glaucoma, suspected glaucoma, and ocular hypertension (raised pressure inside the eye).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Pilocarpine hydrochloride works by directly stimulating cholinergic receptors. This causes the iris sphincter muscle to contract, narrowing the pupil (miosis), and the ciliary muscle to contract, which increases accommodation. It also lowers intraocular pressure by boosting the outflow of aqueous humor while reducing its inflow.
In chronic open-angle glaucoma, the precise way miotic drugs lower intraocular pressure isn't fully understood. It's thought that contraction of the ciliary muscle opens up the spaces between the trabecular fibers, helping aqueous humor drain more easily, while its inflow slows at the same time.
In angle-closure glaucoma, the constricted pupil appears to pull the iris away from the trabecular meshwork, clearing the blockage there and allowing drainage to resume.
Pregnancy & Breastfeeding
Safety in pregnancy has not been established for pilocarpine. No problems have been recorded in human pregnancy so far. Even so, pilocarpine eye drops are absorbed into the body, so the medicine can still reach the whole system.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.