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Community data Updated 23 hours ago

Phenoxymethyl Penicillin [Penicillin V]

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Indications

Pneumonia Bronchitis Sinusitis Pharyngitis Tonsillitis Fever Bacterial Infection Respiratory Tract Infection Skin and Soft Tissue Infection Otitis Media

Phenoxymethyl Penicillin (Penicillin V) is used for mild to moderately severe bacterial infections, as long as the cause is a penicillin susceptible pathogen and the infection responds to oral penicillin. The infections include: Ear, nose and throat infections, such as tonsillitis, pharyngitis, laryngitis, otitis media and sinusitis. Lower respiratory tract infections, such as bronchitis, pneumonia and bronchopneumonia. Infections caused by beta-hemolytic streptococci of group A, such as scarlet fever, erysipelas and rheumatic fever. Skin infections, such as pyodermia, furunculosis, phlegmon, erysipeloid and erythema migrans, but only where the micro-organisms are penicillin-susceptible. Lymphadenitis and lymphangitis of bacterial origin. It is also used for infections of the buccal cavity, gums or jaws. Examples are inflammatory infiltrates, delayed dentition stages II and III, antral fistulae, and secondary bacterial infection with Gram-positive pathogens after virus-induced gingivitis or stomatitis. Phenoxymethyl Penicillin is also given as prophylaxis of scarlet fever, and to prevent recurrences of rheumatic fever. It is used as prophylaxis of infection after dental and oral surgical procedures or dental extractions in certain high risk patients, for example those with congenital cardiac defects, artificial heart valves or rheumatic endocarditis. In some cases, another appropriate antibiotic may be needed in combination.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Phenoxymethyl penicillin, also called penicillin V, is stable in acid and gets absorbed from the upper part of the small intestine. Of its different forms, the potassium salt is absorbed best. You can give it with meals, but absorption is highest when the medicine is taken by mouth at least 1 hour before or 2 hours after a meal.

Phenoxymethyl penicillin is a very convenient way to treat Grampositive infections. Its clear advantage over penicillin G is that gastric acid does not inactivate it.

Pregnancy & Breastfeeding

Phenoxymethylpenicillin crosses the placenta, but when there is a proper indication it can be used at any time during pregnancy. It also passes into breast milk in small amounts. So it can be used while breastfeeding, though the infant may develop diarrhoea and yeast colonization of the mucous membranes.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: The dose of Phenoxymethyl penicillin depends on how sensitive the causative micro-organism is and how severe the infection is. It is then adjusted to the patient's clinical response. Adults take 250 to 500 mg every 6 hours. Children above 1 year take 125 to 250 mg every 6 hours. With the 125 mg/5 ml powder for suspension, the dose is 1 to 2 teaspoonful (5 to 10 ml) every 6 hours. With the 250 mg/5 ml powder for suspension, it is ½ to 1 teaspoonful (2.5 to 5 ml) every 6 hours. Infants below 1 year take 62.5 to 125 mg every 6 hours. With the 125 mg/5 ml powder for suspension, the dose is ½ to 1 teaspoonful (2.5 to 5 ml) every 6 hours, or as prescribed by the physician. Phenoxymethyl penicillin is best taken on an empty stomach, preferably at least 1 hour before a meal or 2 hours after it.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.