Indications
Netarsudil + Latanoprost is used to bring down raised pressure inside the eye (intraocular pressure, or IOP) in people who have open-angle glaucoma or ocular hypertension.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Netarsudil + Latanoprost is a fixed-dose combination of a Rho kinase inhibitor and a Prostaglandin F2 analogue.
Netarsudil is the Rho kinase inhibitor. It works at the cellular level within the trabecular outflow pathway, where it relaxes actin-myosin. This relaxes the trabecular meshwork and the inner wall of Schlemm's canal, and it also decreases episcleral venous pressure (EVP).
Latanoprost is a selective FP receptor agonist. It reduces the intraocular pressure (IOP) by increasing the outflow of aqueous humor through the uveoscleral outflow.
Pregnancy & Breastfeeding
No adequate and well-controlled studies of the Netarsudil and Latanoprost combination have been done in pregnant women, so any risk linked to the medicine is not known. There are also no data on whether Netarsudil or Latanoprost passes into human milk. The effect on a breastfed infant and the effect on milk production are not known either.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.