Nandrolone Decanoate

Indications

Osteoporosis Anemia Cancer

Nandrolone Decanoate injection is used in established osteoporosis and as palliative therapy in disseminated breast cancer in women. It is also given for protein deficiency states that occur after major surgery or trauma, and for anemia due to chronic renal failure. Other uses are aplastic anemia, anemia due to cytotoxic therapy, and chronic debilitating disease in the elderly. The injection is also used in postsurgical and post traumatic catabolism, and during glucocorticosteroid therapy.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Nandrolone Decanoate is an injectable anabolic preparation. The active substance is nandrolone, and the decanoate ester gives a duration of action of about three weeks after injection. It is chemically related to the male hormone. Compared with testosterone, it has a stronger anabolic activity and a weaker androgenic activity. Animal bioassays showed this, and receptor binding studies explain it. Clinical use also confirms the low androgenicity. In humans, nandrolone has been shown to have a positive effect on calcium metabolism and to increase bone mass in osteoporosis. In women with disseminated mammary carcinoma, it has been reported to produce objective regressions for many months. It also has a nitrogen-saving action. Metabolic studies established this effect on protein metabolism, and it is used in treatment where a protein deficiency exists, such as chronic debilitating diseases and after major surgery and severe trauma. In these conditions Nandrolone Decanoate is a supportive adjunct to specific therapies, dietary measures and parenteral nutrition. Androgenic effects (e.g. virilisation) are relatively uncommon at the recommended dosages. The medicine lacks the C 17 alpha-alkyl group, which is associated with liver dysfunction and cholestasis.

Pregnancy & Breastfeeding

Nandrolone Decanoate must not be used during pregnancy, because it can cause masculinization of the foetus. For breastfeeding, there isn't enough data on the use of this medicine in pregnant women or nursing mothers to say whether it could harm the infant or affect milk production.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For established osteoporosis, Nandrolone Decanoate is given as 50 mg every 3 weeks. In disseminated breast cancer in women (palliative therapy), the dose is also 50 mg every 3 weeks. For protein deficiency states after major surgery or trauma, it's 50 mg every 2 to 3 weeks. Anemia due to chronic renal failure needs 50 to 200 mg per week, and aplastic anemia needs 50 to 150 mg per week. For anemia due to cytotoxic therapy, the dose is 200 mg per week. In chronic debilitating disease in the elderly, it's 100 mg. For postsurgical and post-traumatic catabolism, the dose is 25 to 50 mg every 3 weeks, and during glucocorticosteroid therapy it's 50 mg every 2 to 3 weeks. Nandrolone Decanoate should be given by deep intramuscular injection. For the best therapeutic effect, the person also needs adequate amounts of vitamins, minerals and protein, in a calorie-rich diet.