Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Naftopidil is used to treat benign prostatic obstruction, and also the lower urinary tract symptoms (LUTS) that come with benign prostatic hyperplasia (BPH). It doesn't reduce the size of the prostate.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Naftopidil is a selective a-i adrenergic receptor antagonist, and its blocking effect is stronger on the aiD receptor. It works by easing the tension in the smooth muscle of the urethra and the prostate gland, so urine passes more easily. Naftopidil also calms the overactivity of the detrusor muscle.

Pregnancy & Breastfeeding

Pregnancy: No well controlled studies have been done in pregnant women exposed to naftopidil, so a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes is not known.

Lactation: There are no data on whether this combination is present in human milk, what effect it has on a breastfed infant, or what effect it has on milk production.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Take Naftopidil by mouth after a meal. Swallow the tablet whole, without crushing or chewing it. For adults, the usual starting dose is Naftopidil 25 once a day. If this doesn't work well enough, the dose may be raised gradually to 50 to 75 mg once a day, with 1 to 2 weeks between each increase. The doctor may adjust the dose according to the person's age or symptoms. The maximum daily dose is 75 mg. Hepatic impairment: the dose may need to be adjusted in severe hepatic impairment, because this can affect how the drug is metabolised. Renal impairment: no dose adjustment is needed in patients with renal impairment. Use in children and adolescents: safety and effectiveness have not been established in patients below 18 years of age.