Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Naftifine Hydrochloride cream is an allylamine antifungal. Doctors use it to treat interdigital tinea pedis, tinea cruris and tinea corporis when the cause is the organism Trichophyton Rubrum.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Nobody knows exactly how Naftifine Hydrochloride works against fungi. It seems to interfere with sterol biosynthesis by inhibiting the enzyme squalene 2, 3-epoxidase. When this enzyme is blocked, the cells make smaller amounts of sterols, especially ergosterol, and squalene builds up in them as a result.

Pregnancy & Breastfeeding

Naftifine Cream is listed as Pregnancy Category B. There are no adequate and well-controlled studies of Naftifine Cream in pregnant women, and animal reproduction studies don't always predict how humans will respond. So Naftifine Cream should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

It is not known whether this drug passes into human milk. Many drugs do pass into human milk, so caution should be exercised when Naftifine Cream is given to a nursing woman.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Apply a thin layer of Naftifine Hydrochloride Cream once daily to the affected areas and to a half inch margin of healthy skin around them. Keep this up for 2 weeks, or as directed by the physician. Use in children and adolescents: the safety and effectiveness of Naftifine Hydrochloride have been established in the age group of 12 to 17 years with interdigital tinea pedis and tinea cruris.