Lyophilized bacterial lysates of E. coli

Indications

Lyophilized bacterial lysates of E. coli is used as immunotherapy to prevent recurrent lower urinary tract infections. It can also be given alongside other medicines (co-medication) in the treatment of acute urinary tract infections.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Lyophilized bacterial lysates of E. coli is a medicine of biological origin. It works as a stimulant for the immune system and raises the body's natural defences. It can prevent recurrent urinary tract infection, particularly cystitis, and it can also be used alongside other treatments the doctor prescribes (such as antibiotics) during the acute phase of urinary tract infections.

Lyophilized bacterial lysates of E. coli (Lyophilized Bacterial Lysate of Escherichia coli) is taken by mouth as an immunostimulant. Doctors use it to prevent recurrent urinary tract infections (UTIs) and also to treat acute urinary tract infections (UTIs). Both the innate and the adaptive immune responses are enhanced, which bolsters the body's defence against urinary pathogens.

Upon oral administration, the medicine activates innate immune cells (phagocytes and APCs) by stimulating pattern recognition receptors (PRRs) in Peyer's patches (GALT). This starts the maturation of immune cells, and they then migrate to the urinary tract and give localized protection.

Innate and Adaptive Immunity Enhancement:

Innate Immunity: Lyophilized bacterial lysates of E. coli increases cytokine production and adhesion molecules, and it enhances phagocytosis. This contributes to a rapid defence.

Adaptive Immunity: Polyclonal lymphocyte activation is stimulated, which leads to IgA and IgG production. These give humoral protection in the urinary tract and prevent recurrent urinary tract infections (UTIs).

By reinforcing immune defences and preventing inflammation in the bladder, the medicine reduces the recurrence of UTIs. It offers a long-term, immunotherapeutic alternative to traditional antimicrobial treatments.

Pregnancy & Breastfeeding

Pregnancy: it's better to avoid Lyophilized bacterial lysates of E. coli during pregnancy, especially in the first trimester.

Breast-feeding: if you are breast-feeding, use Lyophilized bacterial lysates of E. coli only after you have talked it over with your doctor.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Lyophilized bacterial lysates of E. coli can be used in adults and in children from 4 years of age. The dose depends on the purpose of treatment. For preventive treatment, take 1 capsule per day, preferably in the morning on an empty stomach, for 3 consecutive months (90 days). For treatment of acute episodes, take 1 capsule per day, preferably in the morning on an empty stomach, together with the conventional antimicrobial therapy. Continue until the symptoms disappear, but for at least 10 consecutive days. So far, the use and safety of Lyophilized bacterial lysates of E. coli have not been studied in children under 4 years old. Don't change the prescribed dose on your own. If you think the effect of this medicine is too weak or too strong, talk to your doctor. The efficacy and safety have not been established in children below 4 years.