Lyophilized Bacterial Lysates

Indications

Chronic Obstructive Pulmonary Disease Bronchitis Respiratory Tract Infection

Lyophilized Bacterial Lysates is used as an immunotherapy. Doctors give it to prevent recurrent respiratory tract infections, and also to prevent acute infective exacerbations of chronic bronchitis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

In animals, studies have reported better resistance to experimental infections, stimulation of macrophages and B lymphocytes, and a rise in the immunoglobulins secreted by the cells of the respiratory mucosa. In humans, researchers have seen an increase in the rate of circulating T lymphocytes, an increase in salivary IgA, a higher non-specific response to polyclonal mitogens, and an increase in the mixed lymphocyte reaction.

Absorption: The active ingredient of OM-85 is a bacterial extract made of lyophilised fractions of 21 inactivated bacterial strains. These belong to eight different species: Haemophilus influenzae, Streptococcus pneumoniae, Klebsiella pneumoniae ssp. pneumoniae and ssp. ozaenae, Staphylococcus aureus, Streptococcus pyogenes and sanguinis, and Moraxella (Branhamella) catarrhalis. Because of what the product is, a conventional pharmacokinetic study can't be carried out. The main reasons are the many components in it and the lack of a suitable analytical method. No experimental model is available at present.

Distribution, Metabolism, Elimination: No data available.

Pregnancy & Breastfeeding

There is limited clinical data regarding the use of Lyophilized Bacterial Lysates in pregnant women. Animal studies have not shown any direct or indirect toxicity affecting pregnancy, embryonic development, foetal development and/or post-natal development. Even so, as a precaution, it's preferable to avoid Lyophilized Bacterial Lysates during pregnancy. Regarding breast-feeding, no specific studies have been conducted and no data have been reported. Caution is advised when breast-feeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Adults and adolescents aged over 12: The preventive cycle for recurrent respiratory tract infections is 1 capsule of Lyophilized Bacterial Lysates Adults daily, taken on an empty stomach, for 10 consecutive days per month over 3 consecutive months. It is not meant for treating acute respiratory infections. It is used to prevent them from coming back. The preventive treatment can be started during the acute phase of a respiratory tract infection, together with other treatments. Children aged from 6 months to 12 years: The preventive cycle for recurrent respiratory tract infections is one capsule of Lyophilized Bacterial Lysates Children daily, taken on an empty stomach, for 10 consecutive days per month over 3 consecutive months. Again, this medicine is not for treating acute respiratory infections but for preventing their recurrence. The preventive treatment can be started during the acute phase of a respiratory tract infection, together with other treatments. Note: If a child has difficulty swallowing the capsule, it can be opened and the contents poured into a sufficient quantity of water, fruit juice or milk. The mixture dissolves with gentle stirring. The patient should drink the whole mixture within a few minutes, and it should be stirred well just before drinking. Patients with hepatic or renal disorders: There are no clinical data on the efficacy and safety of Lyophilized Bacterial Lysates in these patients. Children aged under 6 months: Only limited data from clinical studies are available on the use of Lyophilized Bacterial Lysates in children under 6 months of age. As a precaution, its use in this age group is not recommended.