Loperamide + Simethicone

Adults: For adults and children 12 years of age and older, the dose of Loperamide + Simethicone is 2 tablets after the first loose bowel movement, then one tablet or caplet after each loose bowel movement that follows. The maximum is 4 tablets or caplets a day, for no more than 2 days. Children 6 to 11 years of age: this medicine is not recommended for children under 12 years except on the advice of a physician. The proposed dose is 1 tablet after the first loose bowel movement and 1/2 tablet or caplet after each one after that. The daily maximum is 3 tablets or caplets for ages 9 to 11 years, or 2 tablets or caplets for ages 6 to 8 years, and it should not be used for longer than 2 days. Children under 12 years of age: the tablet should be used with special caution, because response varies more in children and swallowing may be difficult. Geriatrics (over 65 years of age): no dose adjustment is needed for the elderly. Renal impairment: no dosage adjustment is needed. Hepatic impairment: no pharmacokinetic data are available for patients with hepatic impairment. The tablet should still be used with caution in these patients because first pass metabolism is reduced. Administration: take the tablet by mouth. It can be taken at any time of day. Caplets should be taken with a full glass of water (250 mL). Chewable tablets should be chewed fully and then swallowed. Drink plenty of clear fluids, which helps prevent the dehydration that may come with diarrhea. Take it only on an empty stomach, which means 1 hour before or 2 hours after a meal.