Lamivudine [For HIV Infection]
Indications
Lamivudine is used to treat HIV infection, and doctors prescribe it together with other antiretroviral medicines.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Lamivudine is a synthetic nucleoside analogue. Inside the cell it is phosphorylated to lamivudine triphosphate. The monophosphate form is then built into viral DNA by hepatitis B virus (HBV) polymerase, and this ends the DNA chain. Lamivudine triphosphate also blocks the RNA and DNA dependent DNA polymerase activities of HIV-1 reverse transcriptase (RT). It is only a very weak inhibitor of mammalian alpha, beta and gamma-DNA polymerases.
Pregnancy & Breastfeeding
Lamivudine is Pregnancy Category C, which means its safety in human pregnancy has not been established.
Lactation: after it is taken by mouth, Lamivudine passes into breast milk at similar concentrations to those found in serum. For that reason, mothers who are taking Lamivudine are advised not to breast-feed their infants.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.