Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Human immunoglobulin-G (IgG) is used in the treatment of primary immunodeficiency. It is also given together with antibiotics in severe bacterial or viral infections. The other conditions it is used for are A-/Hypogammaglobulinemia, Idiopathic Thrombocytopenic Purpura, Guillain-Barre Syndrome and Kawasaki Syndrome.

⚠️ Always consult a registered physician before taking any medicine.

Pregnancy & Breastfeeding

Safety of human immunoglobulin-G in pregnant women has not been established. With human normal immunoglobulin, the possibility of parvovirus B-19 infection cannot be ruled out. If a parvovirus B-19 infection does occur, the fetus may be affected, with abortion, hydrops fetalis or fetal death. So human normal immunoglobulin should be given to a pregnant woman only if the expected benefit justifies the possible risk. The use of this product has not been evaluated in nursing mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Neonates and infants: the dose of human immunoglobulin-G is 5 ml (250 mg)/kg body weight daily on 3 consecutive days. Further infusion may be needed, depending on how the baby progresses clinically. Children and adults: for combined therapy with antibiotics in severe bacterial or viral infections and A-/Hypogammaglobulinemia, the usual dose is 2500 to 5000 mg for adults and 50 to 150 mg/kg for children, given as a single dose. It is given by intravenous drip infusion or by direct intravenous infusion. If it is given as an intravenous injection, inject it very slowly. For Idiopathic Thrombocytopenic Purpura, the usual dose is 200 to 400 mg/kg daily for 5 consecutive days. If an adequate response does not occur, the additional doses are stopped. For Guillain-Barre Syndrome, the usual dose is 400 mg/kg daily for 5 consecutive days. For Kawasaki Syndrome, the usual dose is 400 mg/kg daily for 5 consecutive days (approximately), or 2000 mg daily by intravenous drip infusion. It is recommended to start the treatment within 7 days from the onset of Kawasaki Syndrome.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.