Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Hepatitis B Vaccine [rDNA] is indicated for active immunization against infection caused by all known subtypes of Hepatitis B Vaccine [rDNA] B virus. Hepatitis B Vaccine [rDNA] D (caused by the delta virus) does not occur without Hepatitis B Vaccine [rDNA] B infection, so Hepatitis B Vaccine [rDNA] B vaccination can be expected to prevent Hepatitis B Vaccine [rDNA] D as well. HB-fix is indicated in just the same way, for active immunization against infection caused by all known subtypes of Hepatitis B Vaccine [rDNA] B virus. Immunization is recommended for people of all ages, especially those who are, or will be, at increased risk of exposure to Hepatitis B Vaccine [rDNA] B virus. A baby whose mother is infected can be infected at birth. Children, adolescents and adults can become infected through contact with blood and body fluids through breaks in the skin such as bites, cuts or sores, contact with objects that have blood or body fluids on them such as toothbrushes, razors or monitoring and treatment devices for diabetes, having unprotected sex with an infected person, sharing needles when injecting drugs, or being stuck with a used needle. Others at increased risk include household contacts of people infected with Hepatitis B Vaccine [rDNA] B, residents and staff in institutions for the developmental disabled, kidney dialysis patients, people who travel to countries where Hepatitis B Vaccine [rDNA] B is common, and people with HIV infection. The same goes for persons with hemophilia, thalassemia, sickle cell anemia or cirrhosis, military personnel identified as being at increased risk, morticians and embalmers, prisoners, and users of illicit injectable drugs. Others: police and fire department personnel who render first aid or medical assistance, and any others who, through their work or personal life-style, may be exposed to the Hepatitis B Vaccine [rDNA] B virus.

⚠️ Always consult a registered physician before taking any medicine.

Pregnancy & Breastfeeding

Nobody has studied how the Hepatitis B Vaccine [rDNA] affects the development of the baby in the womb or the ability to have children. For that reason, it should be given during pregnancy only when the risk of infection is high. There isn't enough human data on its use while breastfeeding, and there are no adequate animal reproduction studies either. A nursing mother can be given the vaccine only if it is clearly needed.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For newborns, infants and children up to 19 years of age, the recommended dose of Hepatitis B vaccine (rDNA) is >10 mcg of antigen protein in 0.5 ml. For adults 19 years of age and older, the recommended dose is >20 mcg of antigen in 1 ml. Primary immunization schedule for all ages: the usual schedule is 3 doses. The first dose is given on a chosen date, the second 1 month after the first, and the third 6 months after the first. An accelerated schedule uses 4 doses. The first is given on a chosen date, the second 1 month after the first, the third 2 months after the first, and the fourth 12 months after the first. The accelerated schedule gives protection more quickly and is expected to make it easier for patients to complete the course. A neonate born to a mother who is hepatitis B surface antigen-positive gets 4 doses of 10 micrograms. The first dose is given at birth, together with a Hepatitis B immunoglobulin injection at a separate site. The second dose follows 1 month after the first, the third 2 months after the first, and the fourth 12 months after the first. For travellers departing within 1 month (adults over 18 years), the first dose is given on a chosen date, the second 7 days after the first, the third 21 days after the first, and the fourth 12 months after the first. In renal insufficiency, including haemodialysis patients, adults and children over 16 years get 4 doses of 40 micrograms. The first dose is given at the appropriate date, the second 1 month after the first, the third 2 months after the first, and the fourth 6 months after the first. The immunization schedule and booster doses may need to be adjusted in people with low antibody concentration. Booster vaccinations: for vaccinated people with normal immune status, booster doses of the vaccine have not been established. Booster doses are recommended, however, for haemodialysis patients and other immunocompromised people.