Indications
Follitropin Beta Cartridge is used in women for induction of ovulation and pregnancy in anovulatory infertile women in whom the cause of infertility is functional and not due to primary ovarian failure. Prior checks are needed before starting treatment with Follitropin Beta Cartridge. The woman should have a complete gynecologic and endocrinologic evaluation. Primary ovarian failure should be excluded, and so should the possibility of pregnancy. Tubal patency should be demonstrated, and the fertility status of the male partner should be evaluated. It is also used for pregnancy in normal ovulatory women undergoing controlled ovarian stimulation as part of an In Vitro Fertilization (IVF) or Intracytoplasmic Sperm Injection (ICSI) cycle. Here too, prior evaluation is needed before treatment begins. Women should have a complete gynecologic and endocrinologic evaluation and a diagnosis of the cause of infertility. The possibility of pregnancy should be excluded, and the fertility status of the male partner should be evaluated. In men, Follitropin Beta Cartridge is used for induction of spermatogenesis in men with primary and secondary Hypogonadotropic Hypogonadism (HH) in whom the cause of infertility is not due to primary testicular failure. Before treatment starts, men should have a complete medical and endocrinologic evaluation. Hypogonadotropic hypogonadism should be confirmed and primary testicular failure should be excluded. Serum testosterone levels should be normalized with human chorionic gonadotropin (hCG) treatment. The fertility status of the female partner should also be evaluated.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Women
Follicle-stimulating hormone (FSH) is the active component in Follitropin Beta Cartridge, and the body needs it for normal follicular growth, maturation and the production of gonadal steroids. In women, the FSH level matters a great deal for when follicular development starts and how long it lasts. That in turn decides the timing and the number of follicles that reach maturity. Follitropin Beta Cartridge stimulates ovarian follicular growth in women who do not have primary ovarian failure. Final follicle maturation, the resumption of meiosis and the rupture of the follicle all need to happen, and without an endogenous LH surge they won't happen on their own. So human chorionic gonadotropin (hCG) must be given after treatment with Follitropin Beta Cartridge, once patient monitoring shows that the right follicular development parameters have been reached.
Men
When Follitropin Beta is given together with hCG, it stimulates spermatogenesis in men with hypogonadotropic hypogonadism. FSH, the active component of Follitropin Beta, is the pituitary hormone responsible for spermatogenesis.
Pregnancy & Breastfeeding
Pregnancy: Follitropin Beta Cartridge must not be used in pregnant women, and it gives no benefit during pregnancy.
Lactation: Doctors don't know whether this medicine passes into human milk. So the benefits of breastfeeding for the baby's development and health should be weighed against the mother's clinical need for Follitropin Beta Cartridge. Any possible side effects on the breastfed child, whether from the medicine or from the mother's underlying condition, should be considered as well.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.