Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Fludrocortisone Acetate is taken by mouth as mineralocorticoid replacement therapy. Doctors use it in primary and secondary adrenocortical insufficiency in Addison's disease, in salt losing adrenogenital syndrome, and in postural hypotension.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Fludrocortisone binds to the mineralocorticoid receptor, which is also called the aldosterone receptor. When fludrocortisone activates this receptor, it increases the transport of ions and water in the body. The result is a rise in extracellular fluid volume and blood pressure, and a fall in potassium levels.

Pregnancy & Breastfeeding

Fludrocortisone is pregnancy category C. There are no adequate and well-controlled studies in pregnant women, so doctors recommend it during pregnancy only when there is no alternative and the benefit outweighs the risk.

Lactation: No data exist on whether fludrocortisone passes into human milk. Systemic corticosteroids, though, are known to pass into breast milk, and they could cause growth suppression and/or other adverse effects in nursing infants. The manufacturer advises caution when Fludrocortisone is given to nursing women.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Primary and secondary adrenocortical insufficiency in Addison's disease: the usual dose of Fludrocortisone Acetate ranges from 0.2 mg 3 times weekly to 0.2 mg daily. If hypertension occurs, reduce the dose to 0.05 mg daily. It is given together with cortisone or hydrocortisone. Salt-losing adrenogenital syndrome: 0.1 to 0.2 mg a day. Postural hypotension: diabetic patients with postural hypotension get 0.1 to 0.4 mg daily. Patients whose postural hypotension is secondary to Levodopa therapy get 0.05 to 0.2 mg daily.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.