Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Ferric Carboxymaltose injection is used to treat iron deficiency anemia in adults. It is meant for two groups of patients. The first is people who can't tolerate oral iron, or who haven't had a satisfactory response to it. The second is people who have non-dialysis dependent chronic kidney disease.

⚠️ Always consult a registered physician before taking any medicine.

Pregnancy & Breastfeeding

There are no adequate and well-controlled trials of Ferric Carboxymaltose in pregnant women. So a careful benefit and risk check is needed before it is used in pregnancy, and it should not be used unless clearly necessary.

Animal data suggest that iron released from Ferric Carboxymaltose can cross the placental barrier, and that using it during pregnancy may influence skeletal development in the fetus. If the benefit is judged to outweigh the potential risk for both the mother and the fetus, treatment should be confined to the second and third trimester.

For women who are breast-feeding, the data are limited. Based on them, Ferric Carboxymaltose is unlikely to be a risk to the breast-fed child.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Ferric Carboxymaltose is dosed in three steps. First you work out the iron need, then you calculate and give the dose or doses, and finally you assess the patient after iron repletion. Step 1: Determining the iron need. The iron need for repletion with Ferric Carboxymaltose depends on the patient's body weight and haemoglobin (Hb) level. It is set out as follows. If Hb is <10 g/dl: below 35 kg, 500 mg. From 35 kg to <70 kg, 1500 mg. At 70 kg and over, 2000 mg. If Hb is 10 to 14 g/dl: below 35 kg, 500 mg. From 35 kg to <70 kg, 1000 mg. At 70 kg and over, 1500 mg. If Hb is >14 g/dl: below 35 kg, 500 mg. From 35 kg to <70 kg, 500 mg. At 70 kg and over, 500 mg. Step 2: Calculating and giving the maximum individual iron dose(s). Once the iron need is known, give the appropriate dose or doses of Ferric Carboxymaltose with these limits in mind. A single administration should not exceed 15 mg iron/kg body weight when given by intravenous injection, or 20 mg iron/kg body weight when given by intravenous infusion. It should also not exceed 1,000 mg of iron (20 ml Ferric Carboxymaltose). The maximum recommended cumulative dose is 1000 mg of iron per week. Step 3: Assessment after iron repletion. The clinician should re-assess the patient based on the individual patient's condition. The Hb level should be checked again no earlier than 4 weeks after the final Ferric Carboxymaltose administration, so there is enough time for erythropoiesis and iron utilisation. If the patient needs more iron, recalculate the iron need using the list above.