Indications
Evening Primrose Oil capsule is indicated in premenstrual syndrome symptoms (PMS), benign breast disease and cyclical mastalgia, lactation, atopic, allergic and neurodermatitis, psoriasis, hypertension, rheumatoid arthritis, thrombosis and atopic eczema. It is also used as a dietary aid. It promotes healthy skin and nourishes brittle nails and hair.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Evening Primrose Oil improves the EFA composition of plasma, erythrocytes and platelet lipids, and it improves atocopherol levels in non-diabetic persons and Type 1 diabetic patients. It increases the total fat and EFA contents of mother's milk. In men with low dihomo-gamma-linolenic acid (DGLA) levels, it affects the fatty acid composition of serum lipids and adipose tissue. It also helps maintain normal cellular structures, and it works as a precursor of DGLA, which is the parent of the 1-series prostanoids, and as a precursor of arachidonic acid, which is the parent of the 2-series prostanoids.
The oil supplies gamma-linolenic acid (GLA), and its bioactivity comes primarily from this GLA content. Because it supplies GLA directly, it bypasses the rate-limiting step in the metabolism of LA. After EPO is taken, GLA is absorbed quickly and then converts directly to DGLA and other prostaglandin precursors. It also acts on the prostanoids pathway.
Pregnancy & Breastfeeding
Linolenic acid, GLA and DGLA are important components of human breast milk, so evening primrose oil may be taken while nursing. The World Health Organization (WHO) says pregnant or lactating women should get 5% of their total daily caloric intake from EFAs.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.