Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Escitalopram Oxalate is used in the treatment of major depressive episodes. It is also used in the treatment of panic disorder, with or without agoraphobia. Other uses are the treatment of social anxiety disorder (social phobia), the treatment of generalised anxiety disorder and the treatment of obsessive-compulsive disorder.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Escitalopram is a selective serotonin reuptake inhibitor (SSRI) that you take by mouth. It is the pure S-enantiomer of citalopram, a racemic bicyclic phthalate derivative. Against the R-enantiomer, escitalopram is at least 100 fold more potent at blocking the reuptake of 5-HT. It has no affinity, or only very low affinity, for serotonergic or other receptors, including alpha- and beta-adrenergic, Dopamine, Histamine, Muscarinic and benzodiazepine receptors.

Pregnancy & Breastfeeding

If a pregnant woman is being treated with Escitalopram in the third trimester, the doctor should weigh the possible risks of treatment against the benefits. Escitalopram passes into human breast milk. So the decision to continue or stop either breastfeeding or Escitalopram therapy should take into account the risk of citalopram exposure for the infant and the benefits of Escitalopram treatment for the mother.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Dosage safety: daily doses above 20 mg have not been shown to be safe. Escitalopram Oxalate is given as a single daily dose, and you can take it with or without food. Major depressive episodes: The usual dose is 10 mg once daily. Depending on how the patient responds, the doctor may increase it to a maximum of 20 mg daily. It usually takes 2 to 4 weeks to get an antidepressant response. Once the symptoms have settled, treatment is needed for at least 6 months to consolidate the response. Panic disorder with or without agoraphobia: Start with 5 mg for the first week, then increase to 10 mg daily. The dose can be raised further, up to a maximum of 20 mg daily, depending on the patient's response. Maximum effectiveness comes after about 3 months. Treatment lasts several months. Social anxiety disorder: The usual dose is 10 mg once daily. Symptom relief usually takes 2 to 4 weeks. After that, depending on the patient's response, the dose may be lowered to 5 mg or raised to a maximum of 20 mg daily. Social anxiety disorder is a disease with a chronic course, and 12 weeks of treatment is recommended to consolidate the response. Long-term treatment of responders has been studied for 6 months and can be considered case by case to prevent relapse. The benefits of treatment should be re-evaluated at regular intervals. Social anxiety disorder is a well-defined diagnosis for a specific disorder, and it should not be confused with excessive shyness. Medicine is indicated only if the disorder interferes significantly with professional and social activities. The place of this treatment compared to cognitive behavioural therapy has not been assessed. Pharmacotherapy is part of an overall therapeutic strategy. Generalised anxiety disorder: The initial dose is 10 mg once daily. Depending on the patient's response, it may be increased to a maximum of 20 mg daily. Long-term treatment of responders has been studied for at least 6 months in patients taking 20 mg/day. The benefits of treatment and the dose should be re-evaluated at regular intervals. Obsessive-Compulsive Disorder: The initial dose is 10 mg once daily. Depending on the patient's response, it may be increased to a maximum of 20 mg daily. OCD is a chronic disease, so patients should be treated for long enough to make sure they are symptom-free. The benefits of treatment and the dose should be re-evaluated at regular intervals.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.