Indications
Epalrestat is the active ingredient in Epastat tablet, and it is used for diabetic peripheral neuropathy, the nerve damage that can come with diabetes. It helps ease the numbness and pain that people feel, and it also helps with reduced sense of vibration and abnormal changes in heartbeat. It is given when the glycohemoglobin value is high.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Epalrestat works by specifically blocking the enzyme aldose reductase, which reduces the buildup of sorbitol in nerve tissue. In people with diabetic peripheral neuropathy, this action helps ease symptoms and improves nerve function.
Pregnancy & Breastfeeding
Epalrestat has not been proven safe in pregnant women. It may be given to a pregnant woman, or to a woman who could be pregnant, only when the expected benefit of the treatment is greater than the possible risks. Women should avoid breastfeeding while they are taking epalrestat.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.