Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Elagolix Sodium is used to manage moderate to severe pain linked with endometriosis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Elagolix is a GnRH receptor antagonist. It blocks the body's own GnRH signalling by binding competitively to the GnRH receptors in the pituitary gland. When Elagolix is given, it suppresses luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in a dose-dependent way. This in turn lowers the blood levels of the ovarian sex hormones, estradiol and progesterone.

Pregnancy & Breastfeeding

There isn't much human data on Elagolix in pregnant women, and what exists is too limited to say whether it carries a risk of major birth defects or miscarriage. Exposure to Elagolix early in pregnancy may raise the risk of early pregnancy loss. For this reason, it must not be used by pregnant women. If pregnancy occurs during treatment, Elagolix has to be stopped.

For breastfeeding, nothing is known about whether elagolix or its metabolites pass into human milk. The effects on the breastfed child and on milk production are also unknown.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Rule out pregnancy before starting Elagolix, and begin Elagolix within 7 days of the onset of menses. Initial treatment with Elagolix 150 mg is 150 mg once daily for up to 24 months. If the patient has moderate hepatic impairment, the limit is up to 6 months. Initial treatment with Elagolix 200 mg is 200 mg twice daily for up to 6 months (when dyspareunia is also present). Don't continue Elagolix 200 mg beyond 6 months, because it may decrease bone mineral density (BMD). In moderate to severe hepatic impairment, Elagolix 200 mg is not recommended. Use in children and adolescents: not established in those under 18 years.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.