Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Back pain: Devil's Claw taken by mouth seems to reduce low-back pain, and it seems to work about as well as some non-steroidal anti-inflammatory drugs (NSAIDs). Osteoarthritis: Devil's Claw, taken alone or along with NSAIDs, seems to help decrease osteoarthritis-related pain. Some evidence suggests it works about as well as diacerhein (a slow-acting drug for osteoarthritis that is not available in the U.S.) for improving pain in the hip and knee after 16 weeks of treatment. Some people taking Devil's Claw seem able to lower the dose of NSAIDs they need for pain relief. This evidence comes from a study that used a specific powdered Devil's Claw root product (Harpadol, Arkopharma), which contains 2% of the Devil's Claw ingredient harpagoside (9.5 mg/capsule) and 3% total iridoid glycosides (14.5 mg per capsule). Another specific Devil's Claw extract (Doloteffin, Ardeypharm) has also been used, at 2400 mg/day, providing 60 mg/day of harpagoside.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Devil's claw contains chemicals that might reduce inflammation and swelling, and so ease the pain that comes with them.

Pregnancy & Breastfeeding

Devil's claw is described as possibly safe, but it might harm the developing fetus, so avoid it during pregnancy. It's also best not to use devil's claw while breast-feeding, because not enough is known yet about its safety at that time.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For osteoarthritis, one powdered devil's claw root product (Harpadol, Arkopharm) has been used at 2.6 grams/day. That dose gives a total of 57 mg of harpagoside, one of the active ingredients, and 87 mg of total iridoid glycosides, another active ingredient. A different devil's claw extract (Doloteffin, Ardeypharm) has also been used at 2400 mg/day. For back pain, the dose studied is a specific devil's claw extract (Doloteffin, Ardeypharm) that provides 50 to 100 mg of the active ingredient harpagoside daily.