Indications
Coagulation Factor IX (Recombinant) is a human blood coagulation factor. Adults and children aged 12 years and above who have hemophilia B can use it for on-demand treatment and control of bleeding episodes, for perioperative management, and for routine prophylaxis to reduce the frequency of bleeding episodes. It is not indicated for induction of immune tolerance in patients with hemophilia B.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Hemophilia B is a hereditary, sex-linked disorder of blood clotting. It happens because the body is short of factor IX. People with the condition can bleed into their joints, muscles or internal organs, sometimes without any obvious cause and sometimes after an accident or surgery. Coagulation Factor IX replaces the missing factor IX, so the deficiency is corrected for a time and the tendency to bleed is corrected with it.
Pregnancy & Breastfeeding
There are no data on the use of coagulation factor IX in pregnant women, so any risk linked to the medicine is unknown. Animal reproduction studies have not been done with coagulation factor IX either. In the U.S. general population, the estimated background risk of major birth defect is 2-4% and of miscarriage is 15-20% in clinically recognized pregnancies.
Nothing is known about whether coagulation factor IX passes into human milk, what effect it has on a breastfed infant, or whether it affects milk production. When deciding, weigh the developmental and health benefits of breastfeeding against the mother's clinical need for coagulation factor IX. Also consider any possible adverse effects on the breastfed infant, whether from the medicine or from the mother's underlying condition.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.