Cloxacillin Sodium

Adults: The usual adult dose of Cloxacillin Sodium by mouth is 500 mg four times a day, taken half an hour to one hour before a meal. As an injection into the muscle, the dose is 250 mg every four to six hours. Into a vein, it is 500 mg every four to six hours. These doses can be doubled if needed. Into the pleural cavity, the dose is 500 mg once a day, and the same 500 mg once a day is used when the injection goes into a joint cavity. Children take the medicine by mouth at a usual dose of half the adult dose between 2 and 10 years of age. Under 2 years, the dose is one-quarter of the adult dose. The injection has to be prepared before use. Into the muscle, dissolve 250 mg in 1.5 ml, or 500 mg in 2 ml, of Water for Injection BP. Into a vein, dissolve 500 mg in 5 to 10 ml of Water for Injection BP, then give the solution slowly over three to four minutes. Cloxacillin injection can also be mixed into any fluid that is suitable for infusion, or it can be properly diluted and given slowly through a drip tube over three to four minutes. Into the pleural cavity, dissolve 500 mg in 5 to 10 ml of Water for Injection BP and then give it. Into a joint cavity, dissolve 500 mg in not more than 5 ml of Water for Injection BP or 0.5% lignocaine hydrochloride solution, and give it in the same way.