Indications
Clindamycin and Tretinoin gel is used on the skin to treat acne vulgaris.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Clindamycin + Tretinoin is a combination of clindamycin phosphate, a lincosamide antibiotic, and tretinoin, a retinoid. Clindamycin binds with the 50s ribosomal subunit of susceptible bacteria. This stops the peptide chain from getting longer, because it interferes with the peptidyl transfer, and so bacterial protein synthesis is suppressed. Clindamycin inhibits the activity of Propionibacterium acne and reduces the occurrence of acne. Tretinoin decreases the cohesiveness of follicular epithelial cells and increases the turn over, and this brings the comedones out.
Pregnancy & Breastfeeding
Doctors don't know yet whether Clindamycin or Tretinoin passes into human breast milk. So take special care when applying Clindamycin and Tretinoin to a nursing mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.