Calcium Polystyrene Sulfonate

Adults: Calcium Polystyrene Sulfonate is for oral or rectal use only. Start treatment with the resin as soon as the serum potassium level rises above 6 mmol/L. Adults (including the elderly). Oral: the usual adult dose is 15 g, 3 or 4 times a day. Give the resin by mouth as a suspension in a little water. For a better taste, it can be made into a paste with some sweetened vehicle, but not with orange juice or other fruit juices, because these are known to contain potassium. The amount of fluid usually ranges from 3 to 4 ml per gram of resin. Rectal: if oral use isn't possible, Calcium Polystyrene Sulfonate may be given rectally as a daily retention enema. The suspension is 30 g of resin in 100 ml of 2% methylcellulose and 100 ml of water. Children. Oral: in acute hyperkalemia, give 1 g/kg body weight daily in divided doses. For maintenance therapy the dose may be reduced to 0.5 g/kg body weight daily in divided doses. Rectal: the resin can be given rectally, suspended in a proportional amount of 10% dextrose in water. After the enema has been retained, irrigate the colon so that the resin is properly removed. Neonates. Oral use of Calcium Polystyrene Sulfonate is contraindicated in neonates, so only the rectal route should be considered. Give the minimum effective dose within the range of 0.5 g/kg to 1 g/kg, diluted as for adults, and irrigate well so that the resin is recovered.