Indications
Dobesil capsule is used to treat hemorrhoidal syndrome and microcirculation disorders of arteriovenous origin. It is also used for the clinical signs of chronic venous insufficiency in the lower limbs, which include pain, cramps, paresthesia, edema, stasis and dermatosis. Another use is in microangiopathy, particularly diabetic retinopathy. In superficial thrombophlebitis, Dobesil is given as adjuvant therapy.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Calcium Dobesilate is a vasoactive medicine that is thought to act on the integrity of the endothelium, capillary permeability and blood viscosity. It lowers capillary hyperpermeability and reduces platelet aggregation (the clotting and sticking together of platelets). It also reduces serum viscosity, and this improves blood circulation and the blood supply to tissues and organs.
Pregnancy & Breastfeeding
No studies are available in pregnant women or in animals. It isn't known whether calcium dobesilate crosses the placental barrier in humans, so the medicine should be given only when the expected benefit is judged to outweigh the possible risk to the fetus.
Calcium dobesilate passes into breast milk in very low amounts (0.µ4g/ml after intake of 3×500mg). As a precaution, either the treatment or the breast-feeding should be stopped.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.