Indications
Caffeine Citrate is used to treat apnea of prematurity.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Caffeine is structurally related to other methylxanthines, theophylline and theobromine. It relaxes bronchial smooth muscle, stimulates the CNS and the cardiac muscle, and also acts as a diuretic. How caffeine works in apnea of prematurity is not known, but several mechanisms have been suggested. These include stimulation of the respiratory center, increased minute ventilation, a decreased threshold to hypercapnia, increased response to hypercapnia, increased skeletal muscle tone, decreased diaphragmatic fatigue, increased metabolic rate and increased oxygen consumption. Most of these effects have been attributed to antagonism of adenosine receptors by caffeine, both A1 and A2 subtypes.
Pregnancy & Breastfeeding
Caffeine Citrate falls under Pregnancy Category C. Caffeine passes into breast milk. So if a newborn infant is being treated with Caffeine Citrate, the breast-feeding mother should not take foods, beverages or medicinal products that contain caffeine.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.