Indications
Baloxavir Marboxil is an influenza virus polymerase acidic (PA) endonuclease inhibitor. It is used to treat acute uncomplicated influenza in patients 12 years of age and older who have had symptoms for no more than 48 hours. These patients should either be otherwise healthy or be at high risk of developing influenza-related complications. Baloxavir Marboxil is also used for post-exposure prophylaxis (PEP) of influenza in patients 12 years of age and older after contact with a person who has influenza.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Baloxavir Marboxil is an antiviral that works as a polymerase endonuclease inhibitor. It comes as a film-coated tablet that you take by mouth, and the active component of the tablet is Baloxavir Marboxil. This is a prodrug, which means the body first converts it by hydrolysis into Baloxavir, the form that actually acts against the influenza virus.
Baloxavir blocks the endonuclease activity of the polymerase acidic (PA) protein. This protein is an enzyme specific to the influenza virus, and it sits within the viral RNA polymerase complex, which the virus needs for viral gene transcription. When Baloxavir inhibits it, the influenza virus can't replicate.
Pregnancy & Breastfeeding
There aren't any adequate, well-controlled studies of Baloxavir Marboxil in pregnant women, so we can't say whether it carries a risk of harmful effects on the baby's development. Influenza infection itself during pregnancy is known to carry risks for both the mother and the fetus. As for breastfeeding, there are no data on whether baloxavir marboxil passes into human milk, what effect it might have on a breastfed infant, or whether it changes milk production.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.