Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Atracurium Besilate is used for endotracheal intubation. It also helps with mechanical ventilation in intensive care, and doctors use it as a muscle relaxant during general anaesthesia.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Atracurium works by competing with acetylcholine, the body's chemical messenger, for the cholinergic receptor sites on the motor end-plate. Because it sits on those receptors, acetylcholine can't act there. This effect can be blocked, and the neuromuscular block reversed, by acetylcholinesterase inhibitors such as neostigmine, edrophonium and pyridostigmine.

Pregnancy & Breastfeeding

Atracurium besylate falls under Pregnancy Category C. In rabbits, it was shown to be potentially teratogenic at doses up to approximately one-half the human dose. No adequate and well-controlled studies have been done in pregnant women, so the effect on a human baby is not established. Atracurium should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For adults and children over 1 month old, Atracurium Besilate is started as an IV bolus of 300 to 600 mcg/kg. After that, give further doses of 100 to 200 mcg/kg by IV every 15 to 25 min, or give 5 to 10 mcg/kg/min by infusion if the procedure is a long one. Patients on controlled ventilation in intensive care may be given a higher infusion rate.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.