Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 23 hours ago

Indications

Armodafinil is used to improve wakefulness in adult patients who have obstructive sleep apnea (OSA), narcolepsy or shift work disorder (SWD).

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Armodafinil is an indirect dopamine receptor agonist. It is the R-enantiomer of Modafinil, which is a 1:1 mixture of the R- and S-enantiomers. Armodafinil binds to the dopamine transporter and blocks dopamine reuptake. As a result, neuronal activity rises in the hypothalamus, and activity increases in the hypothalamic wakefulness center (TMN, tuberomammillary nucleus) within the hypothalamic sleep wake switch.

Pregnancy & Breastfeeding

There are no adequate and well controlled studies of Armodafinil in pregnant women. So it should be used during pregnancy only if the possible benefit justifies the possible risk to the fetus.

It isn't known whether Armodafinil or its metabolites pass into human milk. Many drugs do, so caution is needed when Armodafinil is given to a nursing woman.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Adults with obstructive sleep apnea or narcolepsy take Armodafinil as a single dose of 150 mg to 250 mg in the morning. For shift work disorder, the dose is 150 mg as a single dose about 1 hour before the work shift starts. Children: safety and effectiveness have not been established in patients under 17 years of age. Elderly: with age, the body may clear Armodafinil and its metabolites more slowly. So lower doses should be considered for older patients, and they should be monitored closely.

Side Effects & Interactions