Indications
Essential hypertension: Amlodipine Besilate works well on its own for treating hypertension. It can also be used together with other antihypertensive medicines. Angina pectoris: Amlodipine Besilate is indicated for chronic stable angina pectoris, and it works well as the only treatment. It can be combined with other antianginal medicines too. Vasospastic angina: Amlodipine Besilate is indicated for confirmed or suspected vasospastic angina. Doctors can use it alone or alongside other antianginal drugs.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Amlodipine is a dihydropyridine calcium-channel blocker with a long duration of action. Doctors use it to treat hypertension and angina pectoris. It acts on the myocardial cells, the cells of the heart's specialized conducting system, and the cells of vascular smooth muscle.
When Amlodipine is given, the main effect is vasodilation. This brings down peripheral resistance, blood pressure and afterload, and it increases coronary blood flow. There is also a reflex increase in coronary heart rate. Together these changes raise the oxygen supply to the myocardium and increase cardiac output.
Pregnancy & Breastfeeding
Amlodipine is Pregnancy Category C. No adequate and well-controlled studies of Amlodipine have been done in pregnant women, so it should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
It is not known whether Amlodipine passes into human milk. Because this information is missing, it is recommended that breastfeeding be stopped while Amlodipine is being taken.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.