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Antazoline + Tetryzoline eye preparation is used for temporary relief of the signs and symptoms of allergic conjunctivitis. These include conjunctival hyperaemia, chemosis and itching. It can be used in adults and in children above 2 years of age.
Pharmacology
Antazoline is an antihistamine from the ethylenediamine class, and it works as a selective HI antagonist. HI receptors are responsible for several effects, including contraction of smooth muscle and widening of the capillaries, which also become more permeable. Tetryzoline is a sympathomimetic with alpha-adrenergic activity. It narrows the blood vessels, and this reduces redness and edema in allergic conjunctivitis.
Antihistamines block the HI histamine receptor. They are highly effective at relieving itching, but they are not very active against the redness that comes with it. For this reason, products that combine an antihistamine with a vasoconstrictor are well established for the symptomatic relief of allergic eye disease.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and adolescents can use 1 drop of Antazoline + Tetryzoline 2 to 3 times daily, for up to 14 days. For children older than 2 years, no specific studies are available in this age group. Because of possible systemic effects, the dose should not go beyond 1 to 2 drops per day. Children below 2 years of age should not use this medicine.
Don't use the eye drop for longer than 14 days, as this may cause rebound hyperemia and toxic follicular conjunctivitis.
Side Effects
Burning or stinging when the drops go in is the most common side effect of Antazoline + Tetryzoline. It is usually mild and passes quickly.
Cautions & Contraindications
Warnings & Precautions
Use this eye drop with caution in elderly patients who have severe cardiovascular disease, including arrhythmia, or whose hypertension or diabetes is poorly controlled.
Contraindications
Don't use Antazoline + Tetryzoline if you are known to be allergic to Antazoline, Tetryzoline or any of the excipients. It must also not be used together with Monoamine Oxidase Inhibitors (MAOI).
Pregnancy & Breastfeeding
No clinical data are available on pregnancies exposed to Antazoline + Tetryzoline. So the eye drops should only be used if the likely benefit is greater than the risk to the fetus or infant. It isn't known whether either of the active substances passes into breast milk. Take care when using the product while breast-feeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If too much of the Antazoline + Tetryzoline eye solution gets into the eye, flush it out with warm tap water.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Use the Antazoline + Tetryzoline bottle within 30 days after you first open it. Store it at 15-25° C and keep it away from light. Close the bottle tightly right after each use. Keep it out of reach of children.
Drug Interactions
Common questions about Zocare 0.05%+0.04%
What is Zocare 0.05%+0.04% Ophthalmic Solution?
Zocare 0.05%+0.04% Ophthalmic Solution is a medicine that contains Antazoline + Tetryzoline. It is made by Healthcare Pharmaceuticals Ltd. It belongs to the Other ophthalmic preparations group of medicines.
What is Zocare used for?
Antazoline + Tetryzoline eye preparation is used for temporary relief of the signs and symptoms of allergic conjunctivitis. These include conjunctival hyperaemia, chemosis and itching.
What are the side effects of Zocare?
Burning or stinging when the drops go in is the most common side effect of Antazoline + Tetryzoline. It is usually mild and passes quickly.
Can I take Zocare during pregnancy or while breastfeeding?
No clinical data are available on pregnancies exposed to Antazoline + Tetryzoline. So the eye drops should only be used if the likely benefit is greater than the risk to the fetus or infant. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Zocare?
If too much of the Antazoline + Tetryzoline eye solution gets into the eye, flush it out with warm tap water. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Zocare?
Use the Antazoline + Tetryzoline bottle within 30 days after you first open it. Store it at 15-25° C and keep it away from light.
Can I take other medicines with Zocare?
Some medicines can interact with Antazoline + Tetryzoline, for example: Atropine Sulphate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Zocare?
Zocare is a prescription (Rx) medicine. Take it as your doctor advises.