Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Zervira is indicated for:
Pharmacology
Amenamevir blocks the viral helicase-primase complex. This is an enzyme the virus needs to unwind its DNA and to make the primers used when the viral DNA is copied. Older antiviral medicines such as acyclovir and valaciclovir work in a different way, because they target viral DNA polymerase.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Herpes simplex: the usual adult dose of Amenamevir is 200 mg taken by mouth once a day, after a meal.
Recurrent herpes simplex: take a single dose of 1200 mg after a meal, within 6 hours of the first symptoms appearing. Only one dose is needed.
Herpes zoster: the usual adult dose of Amenamevir is 400 mg taken by mouth once a day, after a meal.
Use in children: there are no specific clinical studies that look at the safety and efficacy of Amenamevir in children.
Side Effects
Amenamevir can cause headache, nausea, diarrhea, abdominal pain and skin reactions. Blood and urine tests may also show raised levels of N-acetyl-(M>glucosaminidase and a1-microglobulin. The serious side effects are thrombocytopenia, gingival bleeding and palpitations.
Cautions & Contraindications
Warnings & Precautions
Patients with the following conditions need special monitoring while taking Amenamevir: severe renal impairment, thrombocytopenia, and elderly patients.
Contraindications
Amenamevir should not be given to people with severe renal impairment. It should also not be given to anyone with a history of hypersensitivity to Amenamevir or to any component of the preparation.
Pregnancy & Breastfeeding
Pregnancy: Studies in mice and rabbits found no harmful effects on the mothers or on the development of the fetus at certain doses. The report does not, however, give any specific advice on whether Amenamevir is safe for pregnant women.
Lactation: There is no specific information about using Amenamevir while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Amenamevir below 30°C in a dry place. Keep it away from light and moisture, and keep all medicine out of reach of children.
Drug Interactions
Common questions about Zervira 200 mg
What is Zervira 200 mg Tablet?
Zervira 200 mg Tablet is a medicine that contains Amenamevir. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Anti-viral drugs group of medicines.
What is Zervira used for?
Zervira is used for: Viral Infection.
What are the side effects of Zervira?
Amenamevir can cause headache, nausea, diarrhea, abdominal pain and skin reactions. Blood and urine tests may also show raised levels of N-acetyl-(M>glucosaminidase and a1-microglobulin.
Can I take Zervira during pregnancy or while breastfeeding?
Pregnancy: Studies in mice and rabbits found no harmful effects on the mothers or on the development of the fetus at certain doses. The report does not, however, give any specific advice on whether Amenamevir is safe for pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Zervira?
Store Amenamevir below 30°C in a dry place. Keep it away from light and moisture, and keep all medicine out of reach of children.
Can I take other medicines with Zervira?
Some medicines can interact with Amenamevir, for example: Rifampicin, Midazolam, Ketoconazole. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Zervira is already among the lowest-priced brands of Amenamevir at this strength.
Do I need a prescription for Zervira?
Zervira is a prescription (Rx) medicine. Take it as your doctor advises.