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Oral rehydration salt [rice based] is used when the body loses a lot of fluid and electrolytes quickly. This includes cholera, acute diarrhea and vomiting. It is also used for dehydration, and for severely low concentrations of salts in the blood (severe electrolyte depletion).
Pharmacology
Oral rehydration salt [rice based] contains essential electrolytes and carbohydrate (in the form of processed rice), which a dehydrating patient needs in conditions such as cholera, acute diarrhoea, vomiting and excessive sweating. In a normal healthy intestine, water keeps moving across the intestinal wall. Up to 20 litres of water is secreted and very nearly as much is reabsorbed every 24 hours, and this exchange lets soluble metabolites from digested food pass into the bloodstream. In diarrhoeal disease the balance is upset. Much more water is secreted than is reabsorbed, so the body has a net loss that can be as high as several litres a day. Along with the water, chloride ion (Cl-), extracellular sodium ion (Na+) and intracellular potassium ion (K+) are also lost. This saline replaces those lost electrolytes effectively. The pharmacokinetics and therapeutic values of its components are as follows. Glucose (which comes from rice) helps the absorption of sodium (and so water) on a 1:1 molar basis in the small intestine. Sodium and potassium replace the body's losses of these essential ions during diarrhoea and vomiting. Citrate corrects the acidosis that occurs as a result of diarrhoea and dehydration. Rice, a carbohydrate, is converted to glucose through digestion, and the glucose is then absorbed through the intestinal wall together with salt. Using rice instead of pure glucose in this formula lowers the osmolarity of the solution, so it prevents additional loss of fluid through stools.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The dose of oral rehydration salt [rice based] depends on how severe the dehydration is. Give the following amount after each watery stool. Children from 6 months to 2 years need 50 ml to 100 ml (10 to 20 teaspoonfuls). From 2 years to 9 years, give 100 ml to 200 ml (20 to 40 teaspoonfuls). For those aged 10 years and above, the dose is 250 ml to 500 ml (1 to 2 glassfuls).
Reconstitution Procedure
Preparation for 250 ml saline
Wash both hands with soap before you prepare the saline. Pour 250 ml (one glassful) of hot boiled water into a jar. Then add one full sachet of the saline powder (the one meant for 250 ml water). Mix the powder well in the water until a milky white solution appears. Give the solution to the patient to drink as per the dose.
Preparation for 500 ml saline
Wash both hands with soap before you prepare the saline. Pour 500 ml of hot boiled water (two glassfuls) into a jar. Then add one full sachet of the saline powder (the one meant for 500 ml water). Mix the powder well in the water until a milky white solution appears. Give the solution to the patient to drink as per the dose.
Advice
Discard any reconstituted saline that is left unused 5 hours after preparation. Once the saline is prepared, there is no need to heat or boil it again. Don't use a feeding-bottle. Before each dose, stir the solution with a clean spoon. For babies, a syringe without a needle may be used to put a small amount of saline into the mouth.
Side Effects
Side-effect information is not available for this brand yet.
Cautions & Contraindications
Warnings & Precautions
Take extra care with oral rehydration salt [rice based] if someone has taken a significant overdose. This applies especially to children less than 1 year of age, to patients with an imbalance of salt concentrations in the blood (electrolyte imbalance), and to patients with severely decreased kidney and liver function.
Contraindications
Oral rehydration salt [rice based] should not be used in people with kidney failure that reduces urine production (oliguria) or stops it completely (anuria). It is also not for use when there is an obstruction of the stomach or intestines, or in shock, which means reduced blood flow to vital internal organs. Other situations where it must not be used are severe and continuous vomiting (intractable vomiting), severe dehydration, and severe diarrhea in infants.
Pregnancy & Breastfeeding
Oral rehydration salt (rice based) is recommended during pregnancy and while breastfeeding, because no harmful effects are known when it is used.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Oral rehydration salt [rice based] in a cool, dry place, away from light and moisture.
Common questions about Zenith Rice Saline 250 ml
What is Zenith Rice Saline 250 ml Oral Powder?
Zenith Rice Saline 250 ml Oral Powder is a medicine that contains Oral rehydration salt [rice based]. It is made by Zenith Pharmaceuticals Ltd. It belongs to the Oral electrolytes preparations group of medicines.
What is Zenith Rice Saline used for?
Oral rehydration salt [rice based] is used when the body loses a lot of fluid and electrolytes quickly. This includes cholera, acute diarrhea and vomiting.
Can I take Zenith Rice Saline during pregnancy or while breastfeeding?
Oral rehydration salt (rice based) is recommended during pregnancy and while breastfeeding, because no harmful effects are known when it is used. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Zenith Rice Saline?
Keep Oral rehydration salt [rice based] in a cool, dry place, away from light and moisture.
Do I need a prescription for Zenith Rice Saline?
Zenith Rice Saline is a prescription (Rx) medicine. Take it as your doctor advises.