Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 27% less
These brands contain the same active ingredient (Ulipristal Acetate [For uterine fibroids]). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Yulipris
Other strengths and forms by Healthcare Pharmaceuticals Ltd.
Indications & Uses
Ulipristal Acetate [For uterine fibroids] is given before surgery to treat moderate to severe symptoms of uterine fibroids. These are noncancerous (benign) tumors of the womb (uterus). The medicine is meant for adult women who have not yet reached menopause.
Pharmacology
Ulipristal acetate is a selective progesterone receptor modulator. It works by blocking the receptor for progesterone, a hormone that helps control the growth of the lining of the womb. In some women, progesterone may encourage fibroids to grow, and these can cause symptoms such as heavy uterine bleeding, anaemia and abdominal pain. Once progesterone activity is blocked, the fibroid cells stop dividing and eventually die. This makes the fibroids smaller and eases the symptoms they cause.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Ulipristal acetate is taken by mouth. The usual dose is one 5 mg tablet a day for up to three months. You can repeat the three month course, but only once. Always start the treatment in the first week of the menstrual cycle (that is, during the period bleeding).
Side Effects
Common side effects of Ulipristal Acetate are endometrial thickening, hot flush, headache and uterine haemorrhage.
Cautions & Contraindications
Warnings & Precautions
Ulipristal Acetate [For uterine fibroids] should only be prescribed after a careful diagnosis, and pregnancy must be ruled out before treatment starts. Contraception: Using progestagen-only pills, a progestagen releasing intrauterine device or combined oral contraceptive pills together with Ulipristal Acetate is not recommended. Most women taking a therapeutic dose have anovulation, but a non-hormonal contraceptive method is still recommended during treatment. Endometrial Changes: Endometrial thickening, or Progesterone receptor modulator Associated Endometrial Changes (PAEC), can occur. Ulipristal Acetate has a specific pharmacodynamic action on the endometrium, so the endometrium may become thicker. The thickness goes back to baseline levels once treatment stops. If the thickening is still there more than 3 months after treatment has ended and menstruation has returned, it may need to be investigated in the usual clinical way to exclude underlying conditions. Bleeding Pattern: Patients should be told that treatment usually brings a significant reduction in menstrual blood loss, or amenorrhea, within the first 10 days. If the bleeding stays excessive, they should tell their physician. Asthma Patients: Women with severe asthma that is not well controlled by oral glucocorticoids should not use this medicine, as use in them is not recommended.
Contraindications
Ulipristal Acetate should not be given to patients with hypersensitivity to the active substance or to any of the excipients. It is also contraindicated in pregnancy and breastfeeding. Other patients who must not take it are those with genital bleeding of unknown aetiology or bleeding for reasons other than uterine fibroids, and those with uterine, cervical, ovarian or breast cancer.
Pregnancy & Breastfeeding
Ulipristal acetate is Pregnancy Category X, which means it must not be used during pregnancy. The medicine also passes into human breast milk, so it isn't recommended for women who are breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Hepatic Impairment: Ulipristal Acetate [For uterine fibroids] is not recommended for people with severe liver impairment unless they are closely monitored.
Renal Impairment: Kidney impairment is not expected to change much how the body clears Ulipristal Acetate [For uterine fibroids]. There are no specific studies, though, so the medicine is not recommended for people with moderate or severe kidney impairment unless they are closely monitored.
Overdose
There isn't much experience with an overdose of Ulipristal Acetate [For uterine fibroids]. A small number of subjects were given single doses of up to 200 mg, and some were given 50 mg daily for 10 days in a row. No severe or serious adverse reactions were reported in them.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Ulipristal Acetate below 25° C, and protect it from light and moisture. Keep it out of reach of children.
Common questions about Yulipris 5 mg
What is Yulipris 5 mg Tablet?
Yulipris 5 mg Tablet is a medicine that contains Ulipristal Acetate [For uterine fibroids]. It is made by Healthcare Pharmaceuticals Ltd. It belongs to the Drugs acting on the Uterus group of medicines.
What is Yulipris used for?
Ulipristal Acetate [For uterine fibroids] is given before surgery to treat moderate to severe symptoms of uterine fibroids. These are noncancerous (benign) tumors of the womb (uterus).
What are the side effects of Yulipris?
Common side effects of Ulipristal Acetate are endometrial thickening, hot flush, headache and uterine haemorrhage.
Can I take Yulipris during pregnancy or while breastfeeding?
Ulipristal acetate is Pregnancy Category X, which means it must not be used during pregnancy. The medicine also passes into human breast milk, so it isn't recommended for women who are breastfeeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Yulipris?
There isn't much experience with an overdose of Ulipristal Acetate [For uterine fibroids]. A small number of subjects were given single doses of up to 200 mg, and some were given 50 mg daily for 10 days in a row. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Yulipris?
Store Ulipristal Acetate below 25° C, and protect it from light and moisture. Keep it out of reach of children.
Is there a cheaper medicine with the same ingredient?
Pristil by Incepta Pharmaceuticals Ltd. has the same ingredient and strength for ৳40.00 per unit, compared with ৳55.00 for Yulipris. Ask your doctor or pharmacist before switching.
Do I need a prescription for Yulipris?
Yulipris is a prescription (Rx) medicine. Take it as your doctor advises.