Indications & Uses
Sodium Cromoglicate + Xylometazoline Hydrochloride nasal spray is used to prevent and treat allergic rhinitis, such as hay fever and perennial rhinitis, when the person also has a blocked nose (nasal congestion).
Pharmacology
Xylometazoline Hydrochloride is a sympathomimetic agent with alpha-adrenergic activity. It narrows the blood vessels in the nose (vasoconstriction), and this reduces nasal congestion. So people with a cold can breathe through the nose more easily.
Sodium Cromoglicate usually works through a local effect on the lining of the nose, the nasal mucosa. It stops sensitised mast cells from releasing the mediators of type-l allergic reactions, including histamine and slow reacting substance of anaphylaxis (SRS-A), once the antigen-antibody union has taken place. It doesn't block the binding of IgE to the specific antigen. What it does is suppress the release of substances such as histamine and SRS-A in response to that reaction. The drug also inhibits Type-III (late allergic, Arthers) reactions, though to a lesser extent.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults (including the elderly) and children use one spray in each nostril, four times a day.
Side Effects
No serious side effects have been reported with Sodium Cromoglicate + Xylometazoline Hydrochloride. Some people notice a little irritation inside the nose on the first day of use. In rare cases, wheezing and tightness of the chest have been reported with Sodium Cromoglicate solutions used alone. The Xylometazoline in this combination is given at a lower dose, so any side effects it causes are mild. These include nasal irritation, dryness of the nose, sneezing, headache, insomnia, drowsiness and palpitations.
Cautions & Contraindications
Warnings & Precautions
Using decongestants for a long time, or misusing them, can cause rebound congestion or drug-induced rhinitis.
Contraindications
Don't give this medicine to anyone who is known to be allergic to any of its ingredients.
Pregnancy & Breastfeeding
Sodium Cromoglicate + Xylometazoline Hydrochloride should be used with care during pregnancy, as with any medicine, and most of all in the first trimester.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store below 30°C, away from light and moisture. Keep out of the reach of children.
Common questions about Xylo Plus 2.6 mg+0.0325 mg
What is Xylo Plus 2.6 mg+0.0325 mg Nasal Spray?
Xylo Plus 2.6 mg+0.0325 mg Nasal Spray is a medicine that contains Sodium Cromoglicate + Xylometazoline Hydrochloride. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Mast Cell Stabiliser group of medicines.
What is Xylo Plus used for?
Sodium Cromoglicate + Xylometazoline Hydrochloride nasal spray is used to prevent and treat allergic rhinitis, such as hay fever and perennial rhinitis, when the person also has a blocked nose (nasal congestion).
What are the side effects of Xylo Plus?
No serious side effects have been reported with Sodium Cromoglicate + Xylometazoline Hydrochloride. Some people notice a little irritation inside the nose on the first day of use.
Can I take Xylo Plus during pregnancy or while breastfeeding?
Sodium Cromoglicate + Xylometazoline Hydrochloride should be used with care during pregnancy, as with any medicine, and most of all in the first trimester. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Xylo Plus?
Store below 30°C, away from light and moisture. Keep out of the reach of children.
Do I need a prescription for Xylo Plus?
Xylo Plus is a prescription (Rx) medicine. Take it as your doctor advises.