Informational only — Not medical advice. Always consult a licensed healthcare provider.

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More from Xiotic

Other strengths and forms by Globe Pharmaceuticals Ltd.

Indications & Uses

Xiotic is indicated for:

Pharmacology

Alprazolam belongs to the triazole group within the 1,4-benzodiazepine class of drugs. It works as an anxiolytic, with hypnotic and anticonvulsant properties as well. Its effects are believed to arise from its interaction with the Gamma Aminobutyric Acid (GABA)-benzodiazepine receptor complex. As with all benzodiazepines, it produces a dose-related depressant effect on the CNS, ranging from mild impairment of task performance to hypnosis.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Treatment should begin with 0.25 to 0.5 mg three times daily. Depending on the response, the dose may be increased at intervals of 3 to 4 days, in increments of no more than 1 mg per day. The maximum dose should not exceed 4 mg per day. Occasionally, patients with panic disorder may need as much as 10 mg a day to achieve a successful response; in these cases, periodic reassessment and consideration of dosage adjustment are required.

Dosage should be individualised to achieve the maximum beneficial effect with the lowest possible dose. If side effects occur at the starting dose, the dose may be lowered. When discontinuing therapy, the dosage should be reduced gradually by no more than 0.5 mg every three days.

In elderly patients, or in patients with advanced liver disease, the usual starting dose is 0.25 mg two or three times daily, which may be gradually increased if needed and tolerated.

Patients who are on multiple-dose regimens of Alprazolam 0.25 mg or 0.5 mg should take Alprazolam 1 mg once daily, preferably in the morning. The tablets should be swallowed whole; they should not be chewed, crushed, or broken.

Side Effects

Side effects, when they occur, are usually seen at the start of treatment and tend to go away as the medicine is continued. The most common side effects are drowsiness and light-headedness. Other side effects that may occur include depression, headache, confusion, dry mouth and constipation.

Cautions & Contraindications

Warnings & Precautions

Alprax XR can cause psychological and physical dependence. For this reason, do not increase the dose or stop treatment suddenly without your physician's advice. How long treatment should continue must be decided by your physician. Alprax XR should be used with caution in patients with liver or kidney disease, long-term breathing insufficiency, or sleep apnoea.

Pregnancy & Breastfeeding

Alprazolam falls under pregnancy category D, meaning it carries evidence of risk to the fetus and is best avoided during pregnancy. As with other benzodiazepines, it is thought to pass into breast milk, so mothers who need to take Alprazolam should not breastfeed while using it.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Use in Special Populations

Alprazol has not been shown to be safe or effective in people under 18 years of age.

Overdose

An overdose of Alprazol shows up as sleepiness, confusion, poor coordination, weak reflexes and, in the worst cases, coma. If this happens, general supportive measures should be started, together with immediate gastric lavage.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Store Alprazolam below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.

Drug Interactions

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Common questions about Xiotic 5 mg

What is Xiotic 5 mg Tablet?

Xiotic 5 mg Tablet is a medicine that contains Alprazolam. It is made by Globe Pharmaceuticals Ltd. It belongs to the Benzodiazepine sedatives group of medicines.

What is Xiotic used for?

Xiotic is used for: Depression, Anxiety.

What are the side effects of Xiotic?

Side effects, when they occur, are usually seen at the start of treatment and tend to go away as the medicine is continued. The most common side effects are drowsiness and light-headedness.

Can I take Xiotic during pregnancy or while breastfeeding?

Alprazolam falls under pregnancy category D, meaning it carries evidence of risk to the fetus and is best avoided during pregnancy. As with other benzodiazepines, it is thought to pass into breast milk, so mothers who need to take Alprazolam should not breastfeed while using it. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Xiotic?

An overdose of Alprazol shows up as sleepiness, confusion, poor coordination, weak reflexes and, in the worst cases, coma. If this happens, general supportive measures should be started, together with immediate gastric lavage. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Xiotic?

Store Alprazolam below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.

Can I take other medicines with Xiotic?

Some medicines can interact with Alprazolam, for example: Guaifenesin + Dextromethorphan + Menthol, Dextromethorphan + Phenylephrine + Triprolidine, Posaconazole, Digoxin, Oxazepam. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for Xiotic?

Xiotic is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026