Pricing
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Xalacom is indicated for:
Pharmacology
This medicine contains two active ingredients, Latanoprost and Timolol Maleate. Latanoprost is a prostaglandin analogue. It works by increasing the drainage of aqueous humour out of the eyeball, which decreases the pressure within the eye. Timolol is a beta-blocker. This medicine blocks beta-receptors in various parts of the body. Blocking the beta receptors in the eye reduces the amount of aqueous humour that is produced. Timolol therefore reduces the inflow of aqueous humour into the eyeball and so decreases the pressure within the eyeball.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual dose is one drop in the affected eye or eyes, once a day.
Side Effects
Headache and skin rashes can occur. Eye-related effects include conjunctivitis (inflammation of the eye's lining, with pain and redness) and blepharitis (inflammation of the eyelids), as well as disorders affecting the cornea, the front layer of the eye. Some people notice a change in iris colour (the coloured part of the eye), and the eyelashes may darken, thicken, and grow longer. Hyperaemia (redness from increased blood flow to the eye) can also occur, along with eye pain and irritation such as stinging, burning, and itching.
Cautions & Contraindications
Warnings & Precautions
This medicine may hide the symptoms of low blood sugar, such as a faster heartbeat, trembling and nausea, so people with diabetes should check their blood sugar levels carefully. It may also cause temporary blurred vision, so avoid driving or operating machinery until this clears up. It can mask the symptoms of an overactive thyroid gland (hyperthyroidism), and it may increase sensitivity to allergy-triggering substances as well as the severity of severe allergic reactions (anaphylaxis). Anyone who has an anaphylactic reaction while taking this medicine may need higher than normal doses of adrenaline to treat it. Use with caution in people with a severe form of angina that is not brought on by exertion, absence of the eye's natural lens (aphakia), closed angle glaucoma, diabetes, pigmentary glaucoma (caused by pigment particles building up in the eye's drainage channels), glaucoma due to inflammation inside the eye, glaucoma caused by new blood vessels growing over the iris, heart failure, a history of allergies, severe heart disease, inherited glaucoma, or low blood pressure.
Contraindications
Do not use this medicine if you are allergic to any of its ingredients. It should also be avoided if you have asthma, chronic obstructive lung disease, or any other breathing problem. People with certain heart conditions should not take it either, such as a very slow heart rate, an irregular heartbeat, or heart failure. Breastfeeding and pregnancy are also reasons not to use it. The medicine is contraindicated in cardiogenic shock, which is when the heart cannot keep blood circulating properly. Finally, if you have a serious fault in the electrical pathways of the heart that has reduced how well it works (2nd or 3rd degree heart block), you should not take it.
Pregnancy & Breastfeeding
No reproduction toxicity studies have been conducted with this combination. It should be used during pregnancy only if the potential benefit justifies the potential risk to the unborn baby. Latanoprost and its breakdown products may pass into breast milk, and timolol has also been detected in human milk after eye drop use. Because of the risk of serious side effects in nursing infants, this medicine should be used with caution by breastfeeding mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
No human data is available on overdose with Latanoprost + Timolol. With systemic overdose of Timolol, the symptoms are bradycardia, hypotension, bronchospasm and cardiac arrest. If any of these occur, treatment should be symptomatic and supportive. The ocular effects of Latanoprost at high doses are not known. If an overdose of Latanoprost + Timolol does happen, treatment should be symptomatic.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Before you open it, keep the Latanoprost + Timolol bottle in its box in a refrigerator (2°-8°C), away from light. Once you've opened it, the bottle can stay in its box in a cool place below 25°C. Use the contents within one month of opening the dropper. Keep the medicine out of reach of children.
Drug Interactions
Common questions about Xalacom 0.005%+0.5%
What is Xalacom 0.005%+0.5% Ophthalmic Solution?
Xalacom 0.005%+0.5% Ophthalmic Solution is a medicine that contains Latanoprost + Timolol. It is made by Pfizer. It belongs to the Drugs for miotics and glaucoma group of medicines.
What is Xalacom used for?
Xalacom is used for: Hypertension, Glaucoma.
What are the side effects of Xalacom?
Headache and skin rashes can occur. Eye-related effects include conjunctivitis (inflammation of the eye's lining, with pain and redness) and blepharitis (inflammation of the eyelids), as well as disorders affecting the cornea, the front layer of the eye.
Can I take Xalacom during pregnancy or while breastfeeding?
No reproduction toxicity studies have been conducted with this combination. It should be used during pregnancy only if the potential benefit justifies the potential risk to the unborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Xalacom?
No human data is available on overdose with Latanoprost + Timolol. With systemic overdose of Timolol, the symptoms are bradycardia, hypotension, bronchospasm and cardiac arrest. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Xalacom?
Before you open it, keep the Latanoprost + Timolol bottle in its box in a refrigerator (2°-8°C), away from light. Once you've opened it, the bottle can stay in its box in a cool place below 25°C.
Can I take other medicines with Xalacom?
Some medicines can interact with Latanoprost + Timolol, for example: Latanoprost. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Xalacom?
Xalacom is a prescription (Rx) medicine. Take it as your doctor advises.