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Other strengths and forms by Incepta Pharmaceuticals Ltd.
Indications & Uses
Voriderm is indicated for:
Pharmacology
Voriconazole is a triazole antifungal used to treat serious fungal infections. It works by blocking a fungal enzyme called CYP450-dependent 14-alpha sterol demethylase, which the fungus needs to produce ergosterol, a key component of its cell membrane. By inhibiting this enzyme, voriconazole depletes ergosterol in the fungal cell membrane, disrupting its integrity and stopping the fungus from growing.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Oral voriconazole tablets and powder for suspension should be taken at least one hour before or one hour after a meal. For adults weighing 40 kg or more, the loading dose is 400 mg or 10 ml every 12 hours for the first 24 hours. After that, the maintenance dose is 200 mg or 5 ml twice daily. For adults below 40 kg, the loading dose is 200 mg or 5 ml every 12 hours for the first 24 hours, and the maintenance dose after that is 100 mg or 2.5 ml twice daily. Or, as directed by the registered physician.
Injection
Invasive Aspergillosisd: The loading dose is 6 mg/kg every 12 hours for the first 24 hours. The maintenance dose is 4 mg/kg every 12 hours.
Candidemia in nonneutropenic patients and other deep tissue Candida infections: The loading dose is 6 mg/kg every 12 hours for the first 24 hours. The maintenance dose is 3-4 mg/kg every 12 hours.
Scedosporiosis and Fusariosis: The loading dose is 6 mg/kg every 12 hours for the first 24 hours. The maintenance dose is 4 mg/kg every 12 hours.
Side Effects
The most commonly reported side effects include abdominal pain, anemia, blurred vision, headache, chest pain, nausea, and diarrhea.
Cautions & Contraindications
Warnings & Precautions
Long-term use (whether for treatment or prophylaxis) beyond 180 days needs a careful weighing of benefits against risks. Cases of squamous cell carcinoma of the skin (SCC) have been reported in patients on prolonged Voritec therapy.
Contraindications
Known hypersensitivity to voriconazole or to any of its other ingredients. It should not be given together with terfenadine, astemizole, cisapride, pimozide, quinidine, or sirolimus, as this combination carries a risk of serious adverse reactions. It should also not be co-administered with rifampicin, carbamazepine, long-acting barbiturates, efavirenz, ritonavir, rifabutin, ergot alkaloids, or St. John's Wort, as these combinations risk reducing its effectiveness.
Pregnancy & Breastfeeding
No adequate, well-controlled studies exist in pregnant women. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Voriconazole has not been shown to work in children under 12 years of age.
Overdose
No data on an overdose of Voriconazole has been found.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Voriconazole out of reach of children. Store it in a dry place below 25°C and protect it from light. Voriconazole powder for suspension should be stored between 2° to 8°C.
Drug Interactions
Common questions about Voriderm 200 mg/5 ml
What is Voriderm 200 mg/5 ml Powder For Suspension?
Voriderm 200 mg/5 ml Powder For Suspension is a medicine that contains Voriconazole. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Other Antifungal preparations group of medicines.
What is Voriderm used for?
Voriderm is used for: Fungal Infection.
What are the side effects of Voriderm?
The most commonly reported side effects include abdominal pain, anemia, blurred vision, headache, chest pain, nausea, and diarrhea.
Can I take Voriderm during pregnancy or while breastfeeding?
No adequate, well-controlled studies exist in pregnant women. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Voriderm?
No data on an overdose of Voriconazole has been found. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Voriderm?
Keep Voriconazole out of reach of children. Store it in a dry place below 25°C and protect it from light.
Can I take other medicines with Voriderm?
Some medicines can interact with Voriconazole, for example: Palbociclib, Olaparib, Venetoclax, Brigatinib, Regorafenib Monohydrate, Ibuprofen. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Voriderm?
Voriderm is a prescription (Rx) medicine. Take it as your doctor advises.