Indications & Uses
Vonomax Duo is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Vonoprazan with Amoxicillin is taken every day for 14 days, as a morning dose, a midday dose and a night dose. Two products are used, a Vonoprazan 20 mg tablet and an Amoxicillin 500 mg capsule.
The recommended regimen is as follows. In the morning, take 1 Vonoprazan 20 mg tablet and 2 Amoxicillin 500 mg capsules. At midday, take 2 Amoxicillin 500 mg capsules. At night, take 1 Vonoprazan 20 mg tablet and 2 Amoxicillin 500 mg capsules. You can take these doses with or without food, and the course runs for 14 days.
Side Effects
The most common side effects with Vonoprazan and Amoxicillin (22%) were diarrhea, abdominal pain, vulvovaginal candidiasis and nasopharyngitis.
Cautions & Contraindications
Warnings & Precautions
Hypersensitivity reactions: Serious reactions, and sometimes fatal ones such as anaphylaxis, have been reported with the components of Vonoprazan + Amoxicillin. If a hypersensitivity reaction happens, stop Vonoprazan + Amoxicillin and start treatment straight away (for example, anaphylaxis management). Severe cutaneous adverse reactions (SCAR): Stop the medicine at the first signs or symptoms of SCAR or other signs of hypersensitivity, and consider further evaluation. Clostridioides difficile-associated diarrhea (CDAD): If diarrhea occurs with Vonoprazan + Amoxicillin, it should be evaluated.
Contraindications
Don't give Vonoprazan + Amoxicillin to anyone with a known allergy to Vonoprazan, Amoxicillin or any other beta-lactam, or to any component of the product. It must also not be used with products that contain Rilpivirine.
Pregnancy & Breastfeeding
Animal studies and observational studies in pregnant women who used Clarithromycin point to a concern, so Vonoprazan + Amoxicillin is not recommended in pregnant women. Don't breastfeed while taking Voromax Duo.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric Use
The safety and effectiveness of Vornomax Duo in pediatric patients have not been established.
Renal Impairment
If a patient has mild to moderate renal impairment (eGFR 30 to 89 mL/min), no dose adjustment of Vonomer Duo is recommended. Avoid Vonoprazan + Amoxicillin in patients with severe renal impairment (eGFR <30 mL/min).
Hepatic Impairment
No dose adjustment of Vonomer Duo is recommended in patients with mild hepatic impairment (Child-Pugh A). Avoid Vonoprazan + Amoxicillin in patients with moderate to severe hepatic impairment (Child-Pugh B or C).
Overdose
There is no information on accidental overdose of Vonoprazan + Amoxicillin in humans. If an overdose happens, the patient should contact a doctor, a poison control centre or an emergency room.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Vonoprazan + Amoxicillin below 30°C, in a dry place and away from light. Keep it out of reach of children.
Drug Interactions
Common questions about Vonomax Duo 40 mg + 3000 mg
What is Vonomax Duo 40 mg + 3000 mg Tablet?
Vonomax Duo 40 mg + 3000 mg Tablet is a medicine that contains Vonoprazan + Amoxicillin. It is made by Popular Pharmaceuticals PLC.
What is Vonomax Duo used for?
Vonomax Duo is used for: Helicobacter Pylori Infection.
What are the side effects of Vonomax Duo?
The most common side effects with Vonoprazan and Amoxicillin (22%) were diarrhea, abdominal pain, vulvovaginal candidiasis and nasopharyngitis.
Can I take Vonomax Duo during pregnancy or while breastfeeding?
Animal studies and observational studies in pregnant women who used Clarithromycin point to a concern, so Vonoprazan + Amoxicillin is not recommended in pregnant women. Don't breastfeed while taking Voromax Duo. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Vonomax Duo?
There is no information on accidental overdose of Vonoprazan + Amoxicillin in humans. If an overdose happens, the patient should contact a doctor, a poison control centre or an emergency room. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Vonomax Duo?
Keep Vonoprazan + Amoxicillin below 30°C, in a dry place and away from light. Keep it out of reach of children.
Can I take other medicines with Vonomax Duo?
Some medicines can interact with Vonoprazan + Amoxicillin, for example: Omeprazole, Itraconazole, Allopurinol, Saquinavir, Ritonavir. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Vonomax Duo?
Vonomax Duo is a prescription (Rx) medicine. Take it as your doctor advises.