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These brands contain the same active ingredient (Vildagliptin). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Vilip 50 Tablet is indicated for:
Pharmacology
Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. In people with type 2 diabetes, it is thought to work by slowing the breakdown of incretin hormones. Incretin hormones, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released by the intestine throughout the day, with levels rising after a meal. These hormones are quickly broken down by the enzyme DPP-4. Incretins are part of the body's own system for regulating glucose balance. When blood glucose levels are normal or high, GLP-1 and GIP boost insulin production and release from the beta cells of the pancreas through intracellular signaling pathways involving cyclic AMP. GLP-1 also reduces glucagon release from the pancreas's alpha cells, which lowers glucose production by the liver. By raising and extending the levels of active incretins, vildagliptin increases insulin release and lowers glucagon levels in the blood, acting in a glucose-dependent manner.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Recommended dosing for Vildagliptin is 50 mg or 100 mg once daily as monotherapy. For dual combination therapy with Metformin or a Thiazolidinedione, the dose is 50 mg twice daily, taken in the morning and evening. When combined with a Sulphonylurea, 50 mg is given once daily in the morning. Vildagliptin can be taken with or without food. No dose adjustment is needed for elderly patients or those with mild renal impairment.
Pediatric use: Vildagliptin is not recommended for patients under 18 years of age.
Side Effects
Most people experience only mild, short-lived side effects that do not require stopping treatment. Liver problems are seen rarely. Clinical trials lasting up to and beyond 2 years revealed no additional safety concerns or unexpected risks with the use of Vildagil.
Cautions & Contraindications
Warnings & Precautions
Be careful when giving Vildagil to people aged 75 years and older, as there is limited clinical experience in this age group. Liver function tests (LFTs) should be checked before starting Vildagil, then every three months during the first year, and from time to time after that. If transaminase levels go up, the doctor should repeat the liver function test to confirm the result. After that, liver tests should be done often until the level returns to normal. If AST or ALT stays at 3xULN, Vildagil must be stopped. The same applies to anyone who develops jaundice or other signs of liver problems. Once Vildagil has been stopped and the liver tests are back to normal, Vildagil should not be started again. Because clinical experience is limited, use Vildagil with caution in people with congestive heart failure in New York Heart Association (NYHA) functional class I to II. Do not use it in people with NYHA functional class III or IV.
Contraindications
Vildagliptin should not be given to patients who are hypersensitive to the active substance or to any of the excipients. It is also contraindicated in those with moderate to severe renal impairment, and in people with type 1 diabetes. In hepatic impairment, the medicine must not be used if the pre-treatment alanine aminotransferase (ALT) or aspartate aminotransferase (AST) is more than 3 times the upper limit of normal (ULN).
Pregnancy & Breastfeeding
Vildagliptin should not be used during pregnancy. It should also not be used while breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Vildagliptin below 30°C, away from light and moisture. Always keep it out of reach of children.
Drug Interactions
Common questions about Vilip 50 Tablet 50 mg
What is Vilip 50 Tablet 50 mg Tablet?
Vilip 50 Tablet 50 mg Tablet is a medicine that contains Vildagliptin. It is made by Team Pharmaceuticals Ltd. It belongs to the Dipeptidyl Peptidase-4 (DPP-4) inhibitor group of medicines.
What is Vilip 50 Tablet used for?
Vilip 50 Tablet is used for: Type 2 Diabetes Mellitus, Diabetes Mellitus.
What are the side effects of Vilip 50 Tablet?
Most people experience only mild, short-lived side effects that do not require stopping treatment. Liver problems are seen rarely.
Can I take Vilip 50 Tablet during pregnancy or while breastfeeding?
Vildagliptin should not be used during pregnancy. It should also not be used while breastfeeding. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Vilip 50 Tablet?
Keep Vildagliptin below 30°C, away from light and moisture. Always keep it out of reach of children.
Can I take other medicines with Vilip 50 Tablet?
Some medicines can interact with Vildagliptin, for example: Pioglitazone, Valsartan, Ramipril, Digoxin, Glibenclamide, Simvastatin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Vilip 50 Tablet?
Vilip 50 Tablet is a prescription (Rx) medicine. Take it as your doctor advises.