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Other brands with the same active ingredient
These brands contain the same active ingredient (Verapamil Hydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Verapamil is indicated for:
Pharmacology
Verapamil is an L-type calcium channel blocker with antiarrhythmic, antianginal, and antihypertensive effects. The immediate-release form wears off relatively quickly, so it needs to be taken 3 to 4 times a day, whereas extended-release formulations act longer and can be taken just once daily. Because verapamil reduces the force of the heart's contractions (a negative inotropic effect), it should be avoided in patients with severe left ventricular dysfunction or hypertrophic cardiomyopathy, since this weakening of contractility could worsen these existing conditions.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The dose of Verapamil should be individualized by titration, and the drug should be taken with food. For essential hypertension, the initial dose is 180 mg in the morning. If an adequate response is not obtained with 180 mg of Verapamil, the dose may be titrated in the following manner: 240 mg each morning; 180 mg each morning plus 180 mg each evening; or 240 mg every 12 hours. For angina, the usual dose is 80 mg to 120 mg three times a day. For arrhythmias in digitalized patients, Verapamil should be given at 240 mg to 360 mg in divided doses, depending on the severity of the condition. Divided doses of up to 180 mg a day may occasionally be needed.
Dosage for other forms (1)
Adults: 5 mg slowly by intravenous injection for tachycardias and hypertensive crises, repeated after 5 to 10 minutes if necessary. As a drip infusion to maintain the therapeutic effect, 5 to 10 mg an hour in physiological saline, glucose, laevulose or similar solutions, up to an average total dose of 100 mg a day. Children: newborns, 0.75 to 1 mg (0.3 to 0.4 ml); infants, 0.75 to 2 mg (0.3 to 0.8 ml); children aged 1 to 5 years, 2 to 3 mg (0.8 to 1.2 ml); and children aged 6 to 14 years, 2.5 to 5 mg (1 to 2 ml) of Verapamil, given intravenously depending on age and response. The injection should be given slowly under electrocardiographic control and only until the effect begins. For intravenous infusion in hypertensive crises, the initial dose is 0.05 to 0.1 mg/kg an hour; if the effect proves insufficient, the dose is increased at 30 to 60 minute intervals until twice the dose or more is reached, up to an average total dose of 1.5 mg/kg a day.
Side Effects
Veramil SR is generally well tolerated. The following reactions to orally administered Veramil SR appeared clearly drug-related or occurred at rates greater than 1% in clinical trials involving approximately 5000 patients. Digestive system: constipation, nausea. Cardiovascular system: hypotension, edema, congestive heart failure (CHF), pulmonary edema, bradycardia, AV block. Respiratory system: upper respiratory tract infections. Nervous system: dizziness, headache, fatigue. Skin: rash, flushing. Hepatic: elevated liver enzymes.
Cautions & Contraindications
Warnings & Precautions
Take care with Verapamil Hydrochloride in people who have 1st degree AV block, bradycardia below 50 beats/minutes, hypotension with systolic pressure below 90 mm Hg, atrial fibrillation or flutter, or pre-excitation syndrome occurring at the same time (for example WPW syndrome). The same care applies in heart failure, where the patient must first have been compensated with cardiac glycosides or diuretics. Veramil SR may affect the ability to drive or operate machinery, especially in the early stages of treatment and when alcohol is taken at the same time. Veramil SR also slows the elimination of alcohol markedly, so the effects of alcohol last longer.
Contraindications
Severe left ventricular dysfunction. Hypotension or cardiogenic shock. Sick sinus syndrome, unless the patient has a functioning artificial ventricular pacemaker. Second- or third-degree atrioventricular (AV) block, unless the patient has a functioning artificial pacemaker. Atrial flutter or atrial fibrillation in patients with an accessory bypass tract (e.g., Wolff-Parkinson-White or Lown-Ganong-Levine syndrome). Known hypersensitivity to verapamil hydrochloride.
Pregnancy & Breastfeeding
Verapamil hasn't been thoroughly studied in pregnant women, so doctors generally reserve it for cases where it's clearly necessary. The drug does cross the placenta and can be found in umbilical vein blood at the time of delivery. It also passes into breast milk, which is why breastfeeding is usually stopped for as long as Verapamil treatment continues.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Treatment of a Verapamil Hydrochloride overdose should be supportive. Beta-adrenergic stimulation, or calcium solution given parenterally, may increase calcium ion flux across the slow channel, and both have been used to treat overdose with Verapamil Hydrochloride. Hemodialysis cannot remove the medicine.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Verapamil Hydrochloride below 30°C. Keep it away from light and out of the reach of children.
Drug Interactions
Common questions about Verapamil 80 mg
What is Verapamil 80 mg Tablet?
Verapamil 80 mg Tablet is a medicine that contains Verapamil Hydrochloride. It is made by Albion Laboratories Ltd. It belongs to the Calcium-channel blockers group of medicines.
What is Verapamil used for?
Verapamil is used for: Hypertension, Angina Pectoris, Cardiac Arrhythmia.
What are the side effects of Verapamil?
Veramil SR is generally well tolerated. The following reactions to orally administered Veramil SR appeared clearly drug-related or occurred at rates greater than 1% in clinical trials involving approximately 5000 patients.
Can I take Verapamil during pregnancy or while breastfeeding?
Verapamil hasn't been thoroughly studied in pregnant women, so doctors generally reserve it for cases where it's clearly necessary. The drug does cross the placenta and can be found in umbilical vein blood at the time of delivery. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Verapamil?
Treatment of a Verapamil Hydrochloride overdose should be supportive. Beta-adrenergic stimulation, or calcium solution given parenterally, may increase calcium ion flux across the slow channel, and both have been used to treat overdose with Verapamil Hydrochloride. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Verapamil?
Store Verapamil Hydrochloride below 30°C. Keep it away from light and out of the reach of children.
Can I take other medicines with Verapamil?
Some medicines can interact with Verapamil Hydrochloride, for example: Aspirin, Bisoprolol Fumarate + Amlodipine Besilate, Rivaroxaban, Olaparib, Venetoclax, Talazoparib. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Verapamil?
Verapamil is a prescription (Rx) medicine. Take it as your doctor advises.