Informational only — Not medical advice. Always consult a licensed healthcare provider.

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More from Unicort

Other strengths and forms by G. A. Company Ltd.

Indications & Uses

Unicort is indicated for:

Pharmacology

Hydrocortisone is a corticosteroid valued for its anti-inflammatory and immunosuppressive effects. It reduces inflammation by limiting the migration of polymorphonuclear leukocytes and by reversing the increased capillary permeability that occurs during an inflammatory response. It may also be given as replacement therapy in adrenocortical insufficiency.

Neomycin is an aminoglycoside antibiotic. It binds to the 30S subunit of the bacterial ribosome, blocking protein synthesis and introducing errors in genetic code transcription, which leads to bacterial cell death. It is effective against many gram-negative aerobic bacteria and some gram-positive aerobic bacteria, but it has no activity against fungi, viruses, or most anaerobic bacteria.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Apply as directed by your physician to the affected area.

Side Effects

Burning, itching, and irritation may occur, along with skin thinning, striae, and patches of lighter skin.

Cautions & Contraindications

Warnings & Precautions

Caution in chronic hypertension, DM, epilepsy, and the elderly, and in patients on prolonged therapy. Withdraw gradually; use with caution in pregnancy and lactation.

Contraindications

Contraindicated in viral or fungal skin infections, and in tubercular or syphilitic skin lesions. Should not be used for bacterial infections unless an appropriate antimicrobial is given alongside it.

Pregnancy & Breastfeeding

Pregnancy Category C. Studies in animals have shown harm to the unborn baby, and there are no adequate, well-controlled studies in people. Even so, the possible benefits may justify using this medicine in a pregnant woman despite the possible risks.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Drug Interactions

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Moderate Carbamazepine
Moderate Rifampicin
Moderate Acarbose
Moderate Digoxin
Moderate Vancomycin
Moderate Methotrexate
Moderate Hydrocortisone
Moderate Amphotericin B
Moderate Cisplatin
Moderate Paromomycin
Moderate Pyridostigmine
Moderate Primidone
Moderate Furosemide
Moderate Phenytoin
Moderate Colistin

Common questions about Unicort 500 mg

What is Unicort 500 mg Ointment?

Unicort 500 mg Ointment is a medicine that contains Hydrocortisone Acetate + Neomycin Sulphate. It is made by G. A. Company Ltd. It belongs to the Hydrocortisone & Combined preparations group of medicines.

What is Unicort used for?

Unicort is used for: Pain, Eczema, Urticaria.

What are the side effects of Unicort?

Burning, itching, and irritation may occur, along with skin thinning, striae, and patches of lighter skin.

Can I take Unicort during pregnancy or while breastfeeding?

Pregnancy Category C. Studies in animals have shown harm to the unborn baby, and there are no adequate, well-controlled studies in people. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Can I take other medicines with Unicort?

Some medicines can interact with Hydrocortisone Acetate + Neomycin Sulphate, for example: Carbamazepine, Rifampicin, Acarbose, Digoxin, Vancomycin, Methotrexate. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for Unicort?

Unicort is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026