Trioson
Rx100 mcg+6 mcg+10 mcg • Metered-Dose Inhaler (MDI)
More from Trioson
Other strengths and forms by Eskayef Pharmaceuticals Ltd.
Indications & Uses
Asthma The Beclometasone + Formoterol + Glycopyrronium inhaler is used as maintenance treatment for asthma in adults. It is for those whose asthma is not well controlled on a maintenance combination of a long-acting beta-2 agonist and a medium dose of inhaled corticosteroid, and who have had one or more asthma exacerbations in the previous year. COPD The Beclometasone + Formoterol + Glycopyrronium inhaler is also used as maintenance treatment in adult patients with moderate to severe COPD. It suits people who are not adequately treated by a combination of an inhaled corticosteroid and a long-acting beta-2 agonist, or by a combination of a long-acting beta-2 agonist and a long-acting muscarinic antagonist.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For asthma, the usual dose of Beclometasone + Formoterol + Glycopyrronium in adults (18 years and older) is 2 inhalations twice daily, once in the morning and once in the evening, about 12 hours apart. The recommended starting dose depends on how severe the patient's asthma is.
For COPD, the dose is also 2 inhalations twice daily. This is the maximum, so it should not go above two inhalations twice daily.
Patients should be told to use the inhaler every day, even when they have no symptoms. If symptoms come up between doses, they should use an inhaled short acting beta-2 agonist for quick relief. After each inhalation, the patient should rinse the mouth with water and not swallow it.
Side Effects
The most common side effects of beclometasone + formoterol + glycopyrronium are dysphonia (a hoarse or weak voice), oral candidiasis, muscle spasms and dry mouth. In people with asthma, these effects tend to appear in the first 3 months after treatment starts, and they become less frequent after that.
Cautions & Contraindications
Warnings & Precautions
This inhaler (beclometasone + formoterol + glycopyrronium) is not meant for treating sudden episodes of bronchospasm, or for treating a sudden worsening of a disease. Using it that way can make asthma symptoms worse and cause paradoxical bronchospasm, which can be life threatening. Don't use more than the prescribed dose. Use it with caution in patients with cardiac arrhythmias, especially third-degree atrioventricular block and tachyarrhythmias, and in severe heart disease (particularly acute myocardial infarction, ischaemic heart disease and congestive heart failure). Take the same care in patients with active or quiescent pulmonary tuberculosis, and in those with fungal and viral infections in the airways. Patients with conditions such as hyperthyroidism or diabetes mellitus should also use it with caution. Patients should be advised to keep their rescue inhaler available at all times.
Pregnancy & Breastfeeding
There isn't enough data on the use of Beclometasone Dipropionate, Formoterol Fumarate Dihydrate and Glycopyrronium Bromide in pregnant women. Glucocorticoids are known to cause effects in early pregnancy, and beta-2 sympathomimetics like formoterol have tocolytic effects. So, as a precaution, it is better to avoid this combination during pregnancy and labor.
The medicine should only be used in pregnancy if the expected benefit to the patient outweighs the possible risk to the fetus. Infants and neonates born to mothers who have taken substantial doses should be observed for adrenal suppression.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
An overdose of Beclometasone + Formoterol + Glycopyrronium can cause signs and symptoms that come from each of the three components. These include the effects seen with an overdose of other beta-2 agonists or anticholinergics, and the known class effects of inhaled corticosteroids. If an overdose happens, the symptoms should be treated with supportive care, and the patient should be monitored as needed.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep the inhaler in the refrigerator at 2-8°C until you open it, and don't let it freeze. Once you start using it, keep it below 25°C, and use it for a maximum of 4 months. Keep it away from light and from wet places. Store the inhaler with the mouthpiece down, and keep it out of reach of children.
Drug Interactions
Common questions about Trioson 100 mcg+6 mcg+10 mcg
What is Trioson 100 mcg+6 mcg+10 mcg Metered-Dose Inhaler (MDI)?
Trioson 100 mcg+6 mcg+10 mcg Metered-Dose Inhaler (MDI) is a medicine that contains Beclometasone + Formoterol + Glycopyrronium. It is made by Eskayef Pharmaceuticals Ltd.
What is Trioson used for?
Asthma The Beclometasone + Formoterol + Glycopyrronium inhaler is used as maintenance treatment for asthma in adults. It is for those whose asthma is not well controlled on a maintenance combination of a long-acting beta-2 agonist and a medium dose of inhaled corticosteroid, and who have had one or more asthma exacerbations in the previous year.
What are the side effects of Trioson?
The most common side effects of beclometasone + formoterol + glycopyrronium are dysphonia (a hoarse or weak voice), oral candidiasis, muscle spasms and dry mouth. In people with asthma, these effects tend to appear in the first 3 months after treatment starts, and they become less frequent after that.
Can I take Trioson during pregnancy or while breastfeeding?
There isn't enough data on the use of Beclometasone Dipropionate, Formoterol Fumarate Dihydrate and Glycopyrronium Bromide in pregnant women. Glucocorticoids are known to cause effects in early pregnancy, and beta-2 sympathomimetics like formoterol have tocolytic effects. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Trioson?
An overdose of Beclometasone + Formoterol + Glycopyrronium can cause signs and symptoms that come from each of the three components. These include the effects seen with an overdose of other beta-2 agonists or anticholinergics, and the known class effects of inhaled corticosteroids. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Trioson?
Keep the inhaler in the refrigerator at 2-8°C until you open it, and don't let it freeze. Once you start using it, keep it below 25°C, and use it for a maximum of 4 months.
Can I take other medicines with Trioson?
Some medicines can interact with Beclometasone + Formoterol + Glycopyrronium, for example: Disopyramide. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Trioson?
Trioson is a prescription (Rx) medicine. Take it as your doctor advises.