Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago
Available as: 182 mcg+10.4 mcg+5.5 mcg

Indications & Uses

Trionid is indicated for:

Pharmacology

This medicine combines three drugs: Budesonide, Glycopyrronium Bromide and Formoterol Fumarate Dihydrate. Budesonide is a corticosteroid, and it reduces the swelling and irritation in the lungs. Formoterol and Glycopyrronium are long-acting bronchodilators. They work in different ways to relax the muscles in the airways, which opens the airways wider and makes breathing easier. This helps prevent symptoms such as wheezing, cough, chest tightness and shortness of breath.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Route of administration: this medicine is for oral inhalation only.

Recommended dose: 2 inhalations twice daily, once in the morning and once in the evening. The maximum dose is two inhalations twice daily. After inhaling, the patient should rinse the mouth with water and not swallow it.

Side Effects

People taking budesonide + glycopyrronium bromide + formoterol fumarate most often report upper respiratory tract infection, pneumonia, back pain and oral candidiasis. Influenza, muscle spasms, urinary tract infection, cough, sinusitis and diarrhea are also among the common ones.

Cautions & Contraindications

Warnings & Precautions

This inhaler with Budesonide + Glycopyrronium Bromide + Formoterol Fumarate is not meant for relief of sudden symptoms, so don't use it as rescue therapy for an acute episode of bronchospasm. Don't raise the daily dose above the recommended dose. Patients should not use any other medicine that contains a LABA (Salmeterol, Formoterol Fumarate, Arformoterol Tartrate or Indacaterol), whatever the reason. Take care when this inhaler is considered together with long-term Ketoconazole or other known strong CYP3A4 inhibitors (Ritonavir, Atazanavir, Clarithromycin, Indinavir, Itraconazole, Nefazodone, Nelvfinavir, Saquinavir, Telithromycin). People with COPD often have several risk factors for reduced BMD, so BMD should be assessed before starting Budesonide + Glycopyrronium Bromide + Formoterol Fumarate and again from time to time after that.

Contraindications

Don't give this medicine to anyone who has shown hypersensitivity to Budesonide, Formoterol Fumarate or Glycopyrronium, or to any of the excipients in the product.

Pregnancy & Breastfeeding

Pregnancy: There isn't enough data on the use of Budesonide, Formoterol and Glycopyrronium in pregnant women. Glucocorticoid agents are known to cause effects in the early phase of gestation, and beta-2 sympathomimetic agents such as Formoterol have tocolytic effects. So, as a precaution, it's preferable to avoid this combination during pregnancy and labour. It should be used in pregnancy only if the expected benefit to the patient outweighs the potential risk to the fetus. Infants and neonates born to mothers who received substantial doses should be observed for adrenal suppression.

Lactation: No adequate and well-controlled studies have looked at breastfed children or milk production with Budesonide, Formoterol and Glycopyrronium products, or with its three components, Budesonide, Formoterol Fumarate and Glycopyrronium.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Storage

Don't keep the inhaler in direct sunlight or in a hot place, and don't store it above 30°C. Keep it away from light and from damp places too. Store it with the mouthpiece down, and keep it out of the reach of children. Shake the inhaler well before each use.

Drug Interactions

Open checker →
Moderate Budesonide
Moderate Glycopyrronium
Moderate Ritonavir

Common questions about Trionid 182 mcg+10.4 mcg+5.5 mcg

What is Trionid 182 mcg+10.4 mcg+5.5 mcg Metered-Dose Inhaler (MDI)?

Trionid 182 mcg+10.4 mcg+5.5 mcg Metered-Dose Inhaler (MDI) is a medicine that contains Budesonide + Glycopyrronium Bromide + Formoterol Fumarate. It is made by Eskayef Pharmaceuticals Ltd. It belongs to the Combined bronchodilators group of medicines.

What is Trionid used for?

Trionid is used for: Chronic Obstructive Pulmonary Disease.

What are the side effects of Trionid?

People taking budesonide + glycopyrronium bromide + formoterol fumarate most often report upper respiratory tract infection, pneumonia, back pain and oral candidiasis. Influenza, muscle spasms, urinary tract infection, cough, sinusitis and diarrhea are also among the common ones.

Can I take Trionid during pregnancy or while breastfeeding?

Pregnancy: There isn't enough data on the use of Budesonide, Formoterol and Glycopyrronium in pregnant women. Glucocorticoid agents are known to cause effects in the early phase of gestation, and beta-2 sympathomimetic agents such as Formoterol have tocolytic effects. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store Trionid?

Don't keep the inhaler in direct sunlight or in a hot place, and don't store it above 30°C. Keep it away from light and from damp places too.

Can I take other medicines with Trionid?

Some medicines can interact with Budesonide + Glycopyrronium Bromide + Formoterol Fumarate, for example: Budesonide, Formoterol Fumarate, Glycopyrronium, Ritonavir. Tell your doctor or pharmacist about every medicine you take.

Do I need a prescription for Trionid?

Trionid is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 18 Aug 2026