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Other brands with the same active ingredient
These brands contain the same active ingredient (Tulobuterol Hydrochloride). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Toludil
Other strengths and forms by Techno Drugs Ltd., Satipara, Narshingdi
Indications & Uses
Toludil is indicated for:
Pharmacology
The main way beta-adrenergic drugs work is by stimulating adenyl cyclase, the enzyme that turns adenosine triphosphate (ATP) into cyclic-3',5' adenosine monophosphate (cyclic AMP). This cyclic AMP triggers the cell response that opens up the airways, a process called bronchodilation. Tulobuterol acts very selectively on beta-2 adrenoceptors. This relaxes the smooth muscle of the bronchi, and it has been shown to work well in relieving the symptoms of reversible obstructive airways disease (ROAD), such as bronchial asthma, and also in bronchitis and emphysema.
Some bronchodilators also stimulate beta-1 receptors in the heart, as well as beta-2 receptors. In people who are susceptible, this can cause a fast heartbeat (tachycardia), angina, and possibly arrhythmias. Animal studies and laboratory experiments suggest that tulobuterol is more selective for beta-2 activity than other drugs in this class, so it should cause fewer heart-related side effects.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
the usual oral adult dose of tulobuterol is one 2 mg tablet twice a day. A convenient starting dose for children aged 12 years and over and for adults is 1 mg twice a day, particularly for elderly patients and those with a history of sensitivity to beta-adrenergic agents. Unless drug-related side effects rule it out, the dose may be increased after seven to ten days to 2 mg twice a day if a greater therapeutic response is needed. Although most patients can be maintained on 1 to 2 mg twice daily, differences in patient response and symptom severity may call for further dose adjustment, as with any bronchodilator treatment. If necessary, the adult dose of tulobuterol may therefore be increased to 6 mg a day in divided doses according to clinical response.
Dosage for other forms (2)
Long-term clinical studies have shown that tulobuterol continues to be effective and does not lead to cumulative or toxic side effects. Because the disease varies from patient to patient and dosage needs must be individualized, flexibility in dosing is essential. Long-acting beta agonists should not be used without an asthma controller medication such as an inhaled corticosteroid, and they should be used for the shortest time needed to bring asthma symptoms under control, being discontinued if possible once control is achieved; the patient should then continue on a long-term asthma controller medication such as a corticosteroid.
based on dose-ranging studies in children, the usual dose of tulobuterol syrup (1 mg/5 mL) for children is 40 to 80 mcg/kg/day in two divided doses. Clinical studies in children have found effective doses ranging from 20 to 100 mcg/kg/day. This gives the following age-based recommendations: for children aged one to six years, 0.25 tsp (1.25 mL) to 0.5 tsp (2.5 mL) bid; for children aged six to twelve years, 0.5 tsp (2.5 mL) to 1 tsp (5 mL) bid; for children over twelve years, 1 tsp (5 mL) to 2 tsp (10 mL) bid. These age-based doses may need to be adjusted according to how the patient responds.
Side Effects
Tulobuterol's side effects are broadly similar to those of other sympathomimetic drugs, though it tends to cause fewer cardiovascular effects than some. The most common issue is a dose-related fine tremor of the fingers, which usually eases off with continued use. Less often, oral tulobuterol may cause raised blood pressure, palpitations, chest pain (angina), a fast heartbeat, nausea or vomiting, dizziness, restlessness or overstimulation, difficulty sleeping, and headache.
Cautions & Contraindications
Warnings & Precautions
Long-acting beta agonists should only be used for the long term in people whose asthma cannot be controlled well enough by asthma controller medicines alone. Breton should be used with care in people with diabetes mellitus, hypertension, hyperthyroidism or seizure disorders. Caution is also needed in people with renal failure, because the kidneys are the main route by which the drug leaves the body. The dose may also need to be adjusted for people with impaired liver function, since tulobuterol is normally broken down to a large extent by the liver. As with other sympathomimetic bronchodilators, tulobuterol should be given carefully to people with heart problems, especially those with arrhythmias, coronary insufficiency or myocardial ischaemia.
Contraindications
Tulobuterol should not be used by anyone who is hypersensitive to sympathomimetic amines or to any other ingredient in the formulation.
Pregnancy & Breastfeeding
The safety of this product during pregnancy has not been established. It is also not known whether tulobuterol passes into human breast milk or whether it could harm a newborn. Because of this, as with any medication, using this drug during pregnancy, while breastfeeding, or in women who may become pregnant requires weighing its expected therapeutic benefit against its possible risks to the mother and child.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Drug Interactions
Common questions about Toludil 2 mg
What is Toludil 2 mg Tablet?
Toludil 2 mg Tablet is a medicine that contains Tulobuterol Hydrochloride. It is made by Techno Drugs Ltd., Satipara, Narshingdi. It belongs to the Short-acting selective & β2-adrenoceptor stimulants group of medicines.
What is Toludil used for?
Toludil is used for: Asthma, Chronic Obstructive Pulmonary Disease, Bronchitis.
What are the side effects of Toludil?
Tulobuterol's side effects are broadly similar to those of other sympathomimetic drugs, though it tends to cause fewer cardiovascular effects than some. The most common issue is a dose-related fine tremor of the fingers, which usually eases off with continued use.
Can I take Toludil during pregnancy or while breastfeeding?
The safety of this product during pregnancy has not been established. It is also not known whether tulobuterol passes into human breast milk or whether it could harm a newborn. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Can I take other medicines with Toludil?
Some medicines can interact with Tulobuterol Hydrochloride, for example: Digoxin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Toludil?
Toludil is a prescription (Rx) medicine. Take it as your doctor advises.