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Other strengths and forms by Alco Pharma Limited
Indications & Uses
Tolec is indicated for:
Pharmacology
Ketorolac Tromethamine is a potent analgesic belonging to the non-steroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the cyclooxygenase enzyme system, thereby blocking prostaglandin synthesis. At doses used for pain relief, it shows only a minimal anti-inflammatory effect.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Ketorolac injection may be given as a single dose or as multiple doses, on a regular or as-needed schedule, for managing moderately severe, acute pain that requires analgesia at the opioid level, usually in a postoperative setting. When giving ketorolac injection, the IV bolus must be given over no less than 15 seconds. IM administration should be given slowly and deeply into the muscle. The analgesic effect begins within 30 minutes, with maximum effect in 1 to 2 hours after dosing by IV or IM. The duration of analgesic effect is usually 4 to 6 hours.
Single dose treatment, IM dosing in adults: patients under 65 years of age should receive one dose of 60 mg. Patients over 65 years of age, those who are renally impaired, and those under 50 kg of body weight should receive one dose of 30 mg.
Dosage for other forms (4)
The recommended dose is 10 mg every 4 to 6 hours. It should be used short-term only, up to 7 days, and is not recommended for chronic use. Doses exceeding 40 mg per day are not recommended.
patients under 65 years of age should receive one dose of 30 mg. Patients over 65 years of age, those who are renally impaired, and those under 50 kg of body weight should receive one dose of 15 mg.
IV or IM dosing for children aged 2 to 16 years: for IM dosing, one dose of 1 mg per kg of body weight up to a maximum of 30 mg. For IV dosing, one dose of 0.5 mg per kg of body weight up to a maximum of 15 mg.
patients under 65 years of age should receive a recommended dose of 30 mg ketorolac injection every 6 hours, and the maximum daily dose should not exceed 120 mg. Patients over 65 years of age, renally impaired patients, and patients under 50 kg should receive a recommended dose of 15 mg ketorolac injection every 6 hours, and the maximum daily dose for these groups should not exceed 60 mg. For breakthrough pain, the dose or frequency of ketorolac tromethamine should not be increased.
Conversion from parenteral to oral therapy: ketorolac tablets may be used either as monotherapy or as follow-on therapy to parenteral ketorolac. When ketorolac tablets are used as follow-on therapy to parenteral ketorolac, the total combined daily dose of ketorolac from both oral and parenteral routes should not exceed 120 mg in younger adult patients, or 60 mg in elderly patients, on the day the formulation is changed. On the days that follow, oral dosing should not exceed the recommended daily maximum of 40 mg. Ketorolac IM should be replaced by ketorolac tablets as soon as feasible, and the total duration of combined parenteral and oral treatment should not exceed 5 days.
adults should use 1 drop in each eye 4 times daily.
Side Effects
Common side effects include nausea, vomiting, gastro-intestinal bleeding, melena, peptic ulcer, pancreatitis, anxiety, drowsiness, headache, excessive thirst, fatigue, bradycardia, hypertension, palpitation, chest pain, infertility in females and pulmonary edema.
Cautions & Contraindications
Warnings & Precautions
Take care when giving this medicine to people over 65. The same goes for anyone with an active or suspected peptic ulcer, gastrointestinal bleeding, asthma, or liver problems. For eye drops, if a patient shows signs that the surface of the cornea is breaking down, stop the topical NSAID straight away and keep a close eye on the health of the cornea. Lopadol eye solution should not be put in while the patient is wearing contact lenses.
Contraindications
Ketorolac should not be used by anyone who is allergic to it or to other NSAIDs. It is also not for children under 16 years of age. Doctors don't give it as a preventive painkiller before surgery either.
Pregnancy & Breastfeeding
Ketorolac Tromethamine falls under FDA Pregnancy Category C. For this reason, it is generally best avoided during pregnancy and while breastfeeding, unless a doctor determines that the potential benefit to the mother clearly justifies the possible risk to the baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Ketorolac Tromethamine in a dry place, away from light and heat. Keep it out of the reach of children.
Drug Interactions
Common questions about Tolec 60 mg/2 ml
What is Tolec 60 mg/2 ml IM/IV Injection?
Tolec 60 mg/2 ml IM/IV Injection is a medicine that contains Ketorolac Tromethamine. It is made by Alco Pharma Limited. It belongs to the Drugs used for Rheumatoid Arthritis group of medicines.
What is Tolec used for?
Tolec is used for: Pain, Inflammation.
What are the side effects of Tolec?
Common side effects include nausea, vomiting, gastro-intestinal bleeding, melena, peptic ulcer, pancreatitis, anxiety, drowsiness, headache, excessive thirst, fatigue, bradycardia, hypertension, palpitation, chest pain, infertility in females and pulmonary edema.
Can I take Tolec during pregnancy or while breastfeeding?
Ketorolac Tromethamine falls under FDA Pregnancy Category C. For this reason, it is generally best avoided during pregnancy and while breastfeeding, unless a doctor determines that the potential benefit to the mother clearly justifies the possible risk to the baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Tolec?
Store Ketorolac Tromethamine in a dry place, away from light and heat. Keep it out of the reach of children.
Can I take other medicines with Tolec?
Some medicines can interact with Ketorolac Tromethamine, for example: Polymyxin B Sulfate, Aspirin, Methotrexate, Dexamethasone + Levofloxacin, Enoxaparin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Tolec?
Tolec is a prescription (Rx) medicine. Take it as your doctor advises.