Indications & Uses
Tioren Renacap is indicated for:
Pharmacology
Tiotropium is a long-acting anticholinergic (antimuscarinic) medicine. It binds fairly evenly to all subtypes of muscarinic receptors, from M1 to M5, but its main effect in the airways comes from blocking M3-receptors on the smooth muscle that lines them, which is what allows the airways to widen (bronchodilation). Studies using both human and animal receptors, along with isolated organ tissue, have confirmed that it blocks these receptors in a competitive, reversible way. In laboratory and animal research, it prevented methacholine-induced airway narrowing in a dose-dependent manner, with the effect lasting more than 24 hours. When inhaled, Tiotropium's bronchodilating action occurs mainly at the site where it is deposited in the airways, rather than through effects elsewhere in the body.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults over 18 years: The recommended dose of Tiotropium Dry Powder Inhaler capsule is 18 mcg (1 capsule) taken once daily using the device. The contents of the Tiotropium Dry Powder Inhaler capsules are meant for oral inhalation only and must be used only with the device. No dose adjustment is needed for elderly patients or those with liver or kidney impairment. However, patients with moderate to severe kidney impairment who are given Tiotropium capsule should be watched closely for anticholinergic effects.
Side Effects
Tiotropium's most common side effect is dry mouth. It's usually mild and often eases as treatment continues. Less commonly, individual patients have reported effects consistent with tiotropium's anticholinergic action, including constipation, a faster heartbeat, blurred vision, glaucoma, difficulty urinating, and urinary retention.
Cautions & Contraindications
Warnings & Precautions
Spirium, being an anticholinergic medicine, may aggravate conditions such as narrow-angle glaucoma, an enlarged prostate (prostatic hyperplasia), or bladder-neck obstruction. It should therefore be used cautiously in patients who have any of these conditions.
Contraindications
Tiotropium should not be used by patients who are known to be hypersensitive to atropine or atropine-like drugs, including ipratropium, or to any other ingredient in this product.
Pregnancy & Breastfeeding
Pregnancy Category C. No adequate, well-controlled studies have looked at Tiotropium's use in pregnant women, so it should be used during pregnancy only if the potential benefit to the mother outweighs the possible risk to the fetus. Its safety and effectiveness during labor and delivery have not been studied either.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Taking a high dose of Tiotrop can cause anticholinergic signs and symptoms. That said, 6 healthy volunteers who inhaled a single dose of up to 282 mcg of Tiotrop had no systemic anticholinergic adverse effects. In another study, 12 healthy volunteers inhaled 141 mcg of Tiotrop once daily for several days, and they developed bilateral conjunctivitis and dry mouth.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Tiotropium Dry Powder Inhaler capsules are not for swallowing, so don't take them by mouth. Keep them out of direct sunlight and away from heat, and store them below 30°C. Keep the medicine where children can't reach it.
Drug Interactions
Common questions about Tioren Renacap 18 mcg
What is Tioren Renacap 18 mcg Inhalation Capsule?
Tioren Renacap 18 mcg Inhalation Capsule is a medicine that contains Tiotropium. It is made by Renata PLC. Bhaluka. It belongs to the Anticholinergic bronchodilators group of medicines.
What is Tioren Renacap used for?
Tioren Renacap is used for: Chronic Obstructive Pulmonary Disease, Bronchitis.
What are the side effects of Tioren Renacap?
Tiotropium's most common side effect is dry mouth. It's usually mild and often eases as treatment continues.
Can I take Tioren Renacap during pregnancy or while breastfeeding?
Pregnancy Category C. No adequate, well-controlled studies have looked at Tiotropium's use in pregnant women, so it should be used during pregnancy only if the potential benefit to the mother outweighs the possible risk to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Tioren Renacap?
Taking a high dose of Tiotrop can cause anticholinergic signs and symptoms. That said, 6 healthy volunteers who inhaled a single dose of up to 282 mcg of Tiotrop had no systemic anticholinergic adverse effects. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Tioren Renacap?
Tiotropium Dry Powder Inhaler capsules are not for swallowing, so don't take them by mouth. Keep them out of direct sunlight and away from heat, and store them below 30°C.
Can I take other medicines with Tioren Renacap?
Some medicines can interact with Tiotropium, for example: Cimetidine, Ranitidine. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Tioren Renacap?
Tioren Renacap is a prescription (Rx) medicine. Take it as your doctor advises.