Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Tinizol DS is indicated for:
Pharmacology
Tinidazole is a 5-nitroimidazole derivative whose antimicrobial actions resemble those of metronidazole. It is active against both protozoa (such as Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia) and obligate anaerobic bacteria, working by damaging DNA strands or inhibiting DNA synthesis in these microorganisms.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Prevention of postoperative infections: adults take a single oral dose of 2 g about 12 hours before surgery. For children under 12 years, there are not enough data to recommend a dose for preventing anaerobic infections. Trichomoniasis: a single 2 g oral dose taken with food. Sexual partners should be treated with the same dose at the same time. Giardiasis: adults take a single 2 g dose with food. Children older than three years take a single dose of 50 mg/kg (up to 2 g) with food. Intestinal amebiasis: adults take 2 g per day for 3 days with food. Children older than three years take 50 mg/kg per day (up to 2 g per day) for 3 days with food. Amebic liver abscess: adults take 2 g per day for 3 to 5 days with food. Children older than three years take 50 mg/kg per day (up to 2 g per day) for 3 to 5 days with food. Bacterial vaginosis: non-pregnant adult women take 2 g once daily for 2 days with food, or 1 g once daily for 5 days with food. This medicine should be taken with food, during or immediately after meals.
Side Effects
Reported side effects have generally been infrequent, mild and self-limiting. Gastrointestinal side effects include nausea, vomiting, loss of appetite, diarrhoea and a metallic taste. Hypersensitivity reactions, which are occasionally severe, may occur in rare cases as skin rash, itching, urticaria and angioneurotic oedema. As with related compounds, T-zol may cause transient leukopenia. Other rarely reported side effects are headache, tiredness, furry tongue and dark urine.
Cautions & Contraindications
Warnings & Precautions
Compounds with a similar chemical structure have been linked to various neurological effects, including dizziness, vertigo, poor coordination, and ataxia. If any abnormal neurological signs appear during treatment with T-zol, the medicine should be stopped. Use in Pregnancy and Lactation: T-zol should not be used during the first trimester of pregnancy. Although there is no evidence that it causes harm later in pregnancy, using it during the second and third trimesters should only be considered if the expected benefit to the mother outweighs the possible risk to her and the foetus. T-zol passes into breast milk at levels similar to those found in the blood, and it can remain detectable in breast milk for up to 72 hours after a dose. Breast-feeding should be paused during treatment with T-zol and for 3 days after the final dose.
Contraindications
Tinidazole should not be used in patients who currently have, or have previously had, a blood dyscrasia, as is the case with other structurally similar compounds; that said, clinical and animal studies have not shown any lasting blood abnormalities linked to the drug. It should also be avoided in patients with organic neurological disorders, and it must not be given to anyone with a known hypersensitivity to tinidazole.
Pregnancy & Breastfeeding
Pregnancy Category C. This means that either animal studies have shown some risk to the developing baby (such as birth defects or effects on the foetus), but there are no well-controlled studies in pregnant women, or that no adequate studies have been done in either women or animals. Because of this uncertainty, tinidazole should be used during pregnancy only if the expected benefit to the mother is considered to outweigh the possible risk to the unborn child.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Renal impairment: for patients on haemodialysis, give an extra dose equal to half the usual dose at the end of the dialysis session.
Storage
Keep Tinidazole at room temperature, and store it away from light.
Drug Interactions
Common questions about Tinizol DS 1 gm
What is Tinizol DS 1 gm Tablet?
Tinizol DS 1 gm Tablet is a medicine that contains Tinidazole. It is made by Beacon Pharmaceuticals PLC. It belongs to the Amoebicides group of medicines.
What is Tinizol DS used for?
Tinizol DS is used for: Bacterial Infection, Amoebiasis, Giardiasis.
What are the side effects of Tinizol DS?
Reported side effects have generally been infrequent, mild and self-limiting. Gastrointestinal side effects include nausea, vomiting, loss of appetite, diarrhoea and a metallic taste.
Can I take Tinizol DS during pregnancy or while breastfeeding?
Pregnancy Category C. This means that either animal studies have shown some risk to the developing baby (such as birth defects or effects on the foetus), but there are no well-controlled studies in pregnant women, or that no adequate studies have been done in either women or animals. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Tinizol DS?
Keep Tinidazole at room temperature, and store it away from light.
Can I take other medicines with Tinizol DS?
Some medicines can interact with Tinidazole, for example: Cyclosporine, Oxytetracycline, Metronidazole, Fluorouracil, Cimetidine, Tacrolimus. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Tinizol DS is already among the lowest-priced brands of Tinidazole at this strength.
Do I need a prescription for Tinizol DS?
Tinizol DS is a prescription (Rx) medicine. Take it as your doctor advises.