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Other brands with the same active ingredient
These brands contain the same active ingredient (Tibolone). Same strength and form. Confirm the switch with your doctor or pharmacist.
Tibo
Rx2.5 mg • Tablet
Indications & Uses
Tibo is indicated for:
Pharmacology
Tibolone is a man-made steroid that acts somewhat like estrogen, androgen, and progesterone all at once. After it is taken by mouth, the body quickly breaks it down into three active substances that together produce its effects. Two of these breakdown products (known as the 3α-OH and 3β-OH metabolites) act mainly like estrogen, while the third (the delta-4 isomer) and tibolone itself act mainly like progesterone and androgen. In postmenopausal women, tibolone makes up for the estrogen the body no longer produces, easing menopausal symptoms and helping prevent bone loss after menopause or after the ovaries are removed. Its estrogen-like action benefits the vagina, the bones, and the brain's temperature-control centre, which is why it helps reduce hot flushes, vaginal dryness, and vaginal thinning. Tibolone can also influence mood and sex drive.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The dose is one Tibolone tablet per day, providing 2.5 mg daily. The tablet should be swallowed with some water or another drink, preferably at the same time each day. Improvement of symptoms generally occurs within a few weeks, but the best results are obtained when therapy is continued for at least 3 months.
Starting Tibolone tablet: Women experiencing a natural menopause should begin treatment with Tibolone tablet at least 12 months after their last natural bleed. In the case of a surgical menopause, treatment with Tibolone tablet may begin immediately.
Switching from a sequential or continuous combined HRT (hormone replacement therapy) preparation: If changing from a sequential HRT preparation, treatment with Tibolone should start the day after the prior regimen is completed. If changing from a continuous combined HRT preparation, treatment can start at any time.
Missed dose: A missed dose should be taken as soon as it is remembered, unless it is more than 12 hours overdue. In that case, the missed dose should be skipped, and the next dose should be taken at the usual time. Missing a dose may increase the likelihood of breakthrough bleeding and spotting.
Side Effects
Occasionally, some vaginal bleeding or spotting may occur, especially in the first few months of treatment. Other side effects reported include headache, migraine, swelling (oedema), dizziness, itching, weight gain, nausea, abdominal pain, skin rash, and depression.
Cautions & Contraindications
Warnings & Precautions
Should be used with caution in patients with kidney problems, a history of liver disease, epilepsy, migraine, high cholesterol, impaired carbohydrate (sugar) metabolism, diabetes, or a past episode of cholestatic jaundice.
Contraindications
Contraindicated in pregnancy and breastfeeding; in known or suspected hormone-dependent tumours; in cardiovascular or cerebrovascular disease; in active deep vein thrombosis or other thromboembolic disorders; in vaginal bleeding of unexplained cause; and in severe liver disease.
Pregnancy & Breastfeeding
Tibolone tablet should not be taken during pregnancy. If you become pregnant while using this tablet, stop the treatment straight away. There is no clinical data on pregnancies in which women have taken this tablet. Tibolone tablet must not be used by women who are breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Tibolone has very low acute toxicity in animals, so toxic symptoms aren't expected if several tablets are taken at the same time. In an acute overdose, nausea, vomiting and withdrawal bleeding in females may develop. If necessary, symptomatic treatment can be given.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Tibolone in a cool, dry place and protect it from light. Keep it out of the reach of children.
Drug Interactions
Common questions about Tibo 2.5 mg
What is Tibo 2.5 mg Tablet?
Tibo 2.5 mg Tablet is a medicine that contains Tibolone. It is made by Popular Pharmaceuticals PLC. It belongs to the Drugs for menopausal symptoms: Hormone replacement therapy group of medicines.
What is Tibo used for?
Tibo is used for: Osteoporosis.
What are the side effects of Tibo?
Occasionally, some vaginal bleeding or spotting may occur, especially in the first few months of treatment. Other side effects reported include headache, migraine, swelling (oedema), dizziness, itching, weight gain, nausea, abdominal pain, skin rash, and depression.
Can I take Tibo during pregnancy or while breastfeeding?
Tibolone tablet should not be taken during pregnancy. If you become pregnant while using this tablet, stop the treatment straight away. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Tibo?
Tibolone has very low acute toxicity in animals, so toxic symptoms aren't expected if several tablets are taken at the same time. In an acute overdose, nausea, vomiting and withdrawal bleeding in females may develop. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Tibo?
Store Tibolone in a cool, dry place and protect it from light. Keep it out of the reach of children.
Can I take other medicines with Tibo?
Some medicines can interact with Tibolone, for example: Carbamazepine, Rifampicin, Insulin Detemir. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Tibofem by The ACME Laboratories Ltd. has the same ingredient and strength for ৳20.00 per unit, compared with ৳20.08 for Tibo. Ask your doctor or pharmacist before switching.
Do I need a prescription for Tibo?
Tibo is a prescription (Rx) medicine. Take it as your doctor advises.